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Bone and Cytokine Markers Associated With Bone Disease in Systemic Mastocytosis

Rama, TA; Henriques, AF; Matito, A; Jara-Acevedo, M; Caldas, C; Mayado, A; Muñoz-González, JI; Moreira, A; Cavaleiro Rufo, J; García-Montero, A

Background Mastocytosis encompasses a heterogeneous group of diseases characterized by tissue accumulation of clonal mast cells, which frequently includes bone involvement. Several cytokines have been shown to play a role in the pathogenesis of bone mass loss in systemic mastocytosis (SM), but their role in SM-associated osteosclerosis remains unknown. Objective To investigate the potential association between ...


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