4 documents found, page 1 of 1
Bone and Cytokine Markers Associated With Bone Disease in Systemic Mastocytosis
Rama, TA; Henriques, AF; Matito, A; Jara-Acevedo, M; Caldas, C; Mayado, A; Muñoz-González, JI; Moreira, A; Cavaleiro Rufo, J; García-Montero, ABackground Mastocytosis encompasses a heterogeneous group of diseases characterized by tissue accumulation of clonal mast cells, which frequently includes bone involvement. Several cytokines have been shown to play a role in the pathogenesis of bone mass loss in systemic mastocytosis (SM), but their role in SM-associated osteosclerosis remains unknown. Objective To investigate the potential association between ...
Mast Cell Activation Syndromes: Comparison Between Two Scoring Models to Predic...
Rama, TA; Torrado, I; Henriques, AF; Sánchez-Muñoz, L; Jara-Acevedo, M; Navarro-Navarro, P; Caldas, C; Mayado, A; Muñoz-González, J; García-Montero, ABACKGROUND: The Red Espanola de Mastocitosis (Spanish Network on Mastocytosis) score (REMAs) and the National Institutes of Health idiopathic clonal anaphylaxis score (NICAS) were developed for more efficient screening of mast cell (MC) clonality in MC activation syndromes. In a limited idiopathic anaphylaxis case series, the NICAS showed higher accuracy compared with the REMAs. OBJECTIVE: To compare the perfor...
Mastocytosis presenting with mast cell-mediator release-associated symptoms eli...
Rama, TA; Morgado, JM; Henriques, A; Escribano, L; Alvarez-Twose, I; Sanchez-Muñoz, L; Moreira, A; Romão, J; Órfão, A; Matito, ABackground: Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo-oxygenase (COX), subsequent depletion of prostaglandin E2 and release of leukotrienes. Objectives: Here, we aimed at determining the prevalence of mast cell (MC) mediator release symptoms triggered by NSAIDs ...
Abnormal NK cell lymphocytosis detected after splenectomy: association with rep...
Granjo, E; Lima, M; Fraga, M; Santos, F; Magalhães, C; Queirós, ML; Moreira, I; Rocha, S; Silva, AS; Rebelo, I; Quintanilha, A; Ribeiro, ML; Candeias, JAbnormal NK cell lymphocytosis detected after splenectomy: association with repeated infections, relapsing neutropenia, and persistent polyclonal B-cell proliferation. Granjo E, Lima M, Fraga M, Santos F, Magalhães C, Queirós ML, Moreira I, Rocha S, Silva AS, Rebelo I, Quintanilha A, Ribeiro ML, Candeias J, Orfão A. Department of Hematology, Hospital S. João, Porto, Portugal. npp46740@mail.telepac.pt Abstract W...