5 documents found, page 1 of 1
Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepa...
Cayuela,Natalie Chaves; Negreti,Gabrielly Pascoa; Rasslan,Roberto; Koike,Marcia Kiyomi; Montero,Edna Frasson de SouzaAbstract Purpose: To evaluate the oxidative stress, resulting from ischemia and hepatic reperfusion, in mice with non-alcoholic hepatic steatosis and steatohepatitis. Methods: C57BL/6 male mice were used. Part of them were ob/ob mice, and the other part was fed with standard or MCD diets - this last used to develop steatohepatitis. The animals - MCD-I/R, ob/ob-I/R and I/R groups - were submitted to 30 minutes o...
Bacterial translocation and mortality on rat model of intestinal ischemia and o...
Costa,Rafael Izar Domingues da; Rasslan,Roberto; Koike,Marcia Kiyomi; Utiyama,Edivaldo Massazo; Montero,Edna Frasson de SouzaAbstract Purpose: To develop an experimental model of intestinal ischemia and obstruction followed by surgical resection of the damaged segment and reestablishment of intestinal transit, looking at bacterial translocation and survival. Methods: After anesthesia, Wistar rats was subject to laparotomy, intestinal ischemia and obstruction through an ileal ligature 1.5cm of ileum cecal valve; and the mesenteric ves...
Management of infected pancreatic necrosis: state of the art
Rasslan,Roberto; Novo,Fernando da Costa Ferreira; Bitran,Alberto; Utiyama,Edivaldo Massazo; Rasslan,SamirABSTRACT Pancreatic necrosis occurs in 15% of acute pancreatitis. The presence of infection is the most important factor in the evolution of pancreatitis. The diagnosis of infection is still challenging. Mortality in infected necrosis is 20%; in the presence of organic dysfunction, mortality reaches 60%. In the last three decades, there has been a real revolution in the treatment of infected pancreatic necrosis...
Pentoxifylline associated to hypertonic saline solution attenuates inflammatory...
Marques,Geraldo Magela Nogueira; Rasslan,Roberto; Belon,Alessandro Rodrigo; Carvalho,Juliana Gonçalves; Felice Neto,Raphael; Rasslan,SamirPURPOSE: To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline.METHODS:It was allocated into four groups (n=6), 24 male Wistar rats (200 to 250g) and submitted to intestinal ischemia for 40 min and reperfusion for 80 min: IR (did not receive any treatment); HS group (Hypertonic Saline, 4ml/kg-IV); PTX group (Pe...
Fístula linfática após esofagectomia: o que fazer?
Rasslan,Roberto; Lopes,Luiz Roberto; Toro,Ivan Felizardo Contrera; Seabra,José Cláudio; Santos-Filho,Pedro Augusto Bisi dos; Silva,Leonardo G. daRACIONAL: As lesões do ducto torácico ocasionando quilotórax são pouco freqüentes e ocorrem durante procedimentos torácicos e traumas, tais como esofagectomias, procedimentos cirúrgicos mediastinais e pleuro-pulmonares. A operação está indicada se não houver resolução espontânea. OBJETIVO: Analisar a fístula linfática como complicação de esofagectomias para doenças malignas e benignas. MÉTODOS: Sete doentes com...