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The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in ...
Vianna, Júlia Silveira; Ramis, Ivy Bastos; Ramos, Daniela Fernandes; Gastal, Otávio Leite; Silva, Renato Azevedo da; Gonçalves, Carla VitolaIn this study, we evaluated the mutations of Helicobacter pylori associated with resistance to clarithromycin and levofloxacin. Furthermore, based on the proposed interaction between antimicrobial resistance and pathogenicity, we correlated the mutation profiles of the strains with the presence of the pathogenicity gene cagA. We analyzed 80 gastric biopsy specimens from H. pylori-infected patients for point mut...
Data: 2018
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Origem: Oasisbr