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Spray drying as a viable process to produce nano-hydroxyapatite/chitosan (n-HAp...
G. Ruphuy; A. Saralegi; J. C. Lopes; M. M. Dias; M. F. BarreiroIn this work nano-hydroxyapatite/chitosan (n-HAp/CS) hybrid microparticles were prepared by spray drying following a methodology where, in a first step, aqueous nanodispersions of n-HAp in the presence of chitosan were produced by fast stirring at pH values below and above chitosan pKa (5.5 and 7.0, respectively). The mixing system used allowed the production of homogeneous and stable nanodispersions, and the s...
Date: 2016
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Origin: Repositório Aberto da Universidade do Porto