Purpose: Neoadjuvant systemic therapy with dual HER2-blockade, trastuzumab and pertuzumab, combined with chemotherapy has become a standard approach in patients with HER2-positive (HER2+) breast cancer (BC). However, the variability in treatment outcomes, such as pathological complete response (pCR) or relapse rates, underscores the need to identify predictive factors to optimize therapeutic strategies. This st...
To identify the most used dosimeters for monitoring ultraviolet radiation (UVR) and analyze their reliability and cost for individual UV exposure monitoring, this study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. An extensive search of the PubMed, Scopus, and Web of Science databases, covering 2005–2023, was conducted, including examining reference lists of retrie...
Survivors of sexual abuse and their families seek help from criminal law enforcement agencies and health professionals to obtain justice and health care. Many communities have implemented multi-professional collaborative models so that the victim’s well-being is assured and the truth is established. However, there is a general lack of evidence on how to best articulate these teams with the healthcare profession...
Introdução: A utilização de Grupos Focais no Desenvolvimento e Avaliação de Programas está descrita na literatura (Magill, 1993; Tümen-Akyıldız & Ahmed, 2021). Objetivos: Identificação de barreiras e facilitadores do desempenho dos serviços do SNSA em Cabinda. Material e Métodos: Estudo descritivo, exploratório (qualitativo), com formação de um Grupo Focal (GF), com o objetivo de identificar problemas prior...
Vol. 34 No. 7-8 (2021): July-August
foi entender como o exercício nos membros inferiores afeta a perfusão num grupo de indivíduos saudáveis. O estudo envolveu uma amostra de conveniência de dezoito indivíduos saudáveis, de ambos os sexos (32,8 ± 12,7 anos) previamente selecionados. Os procedimentos respeitaram todos os princípios da boa prática clínica. A perfusão sanguínea foi avaliada na região dorsal de ambos os pés por fluxometria de laser Do...
Physiological perfusion asymmetries in the lower limb are known, although poorly understood, as are asymmetries reported in plantar pressure and stance. This preliminary study aims to explore potential relationships between perfusion and pressure variables in humans. A convenience sample of eight healthy individuals (25.25 ± 5.37 years old) of both sexes, was selected. Chosen variables were perfusion, plantar p...
News of sexual abuse against children is increasingly common. This paper aims to describe the historical and social progress of sexual violence against children through a narrative review of the literature, with the goal of understanding how health systems deal with sexual violence against children, as well as to identify the costs to society and to children's personal lives. The history and latest global and n...
Kefir, a traditional fermented food, has numerous health benefits due to its unique chemical composition, which is reflected in its excellent nutritional value. Physicochemical and microbial composition of kefir obtained from fermented milk are influenced by the type of the milk, grain to milk ratio, time and temperature of fermentation, and storage conditions. It is crucial that kefir characteristics are maint...
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