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Bone marrow mesenchymal stem cells' secretome exerts neuroprotective effects in...
Pinheiro, Bárbara Filipa Mendes; Anjo, Sandra I.; Manadas, Bruno; da Silva, Jorge D.; Marote, Ana Maria Franco Aveiro; Behie, Leo A.; Teixeira, Fábio G.Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism behind dopaminergic cell death is still not completely understood and, so far, no cure or neuroprotective treatment for PD is available. Recent studies have brought attention to the variety of bioactive molecules produced by mesenchymal stem cells (MSCs), g...
Date: 2019
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Origin: RepositóriUM - Universidade do Minho