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The Dynamics of the Pulmonary Microbiome During Mechanical Ventilation in the I...

Zakharkina, T; Martin-Loeches, I; Matamoros, S; Povoa, P; Torres, A; Kastelijn, JB; Hofstra, JJ; de Wever, B; de Jong, M; Schultz, MJ; Sterk, PJ

RATIONALE: Ventilator-associated pneumonia (VAP) is the most common nosocomial infections in patients admitted to the ICU. The adapted island model predicts several changes in the respiratory microbiome during intubation and mechanical ventilation. OBJECTIVES: We hypothesised that mechanical ventilation and antibiotic administration decrease the diversity of the respiratory microbiome and that these changes are...


ARIA 2016: Care pathways implementing emerging technologies for predictive medi...

Bousquet, J; Hellings, PW; Agache, I; Bedbrook, A; Bachert, C; Bergmann, KC; Bewick, M; Bindslev-Jensen, C; Bosnic-Anticevitch, S; Bucca, C; Caimmi, DP

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA-disseminated and im...


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