3 documents found, page 1 of 1
Canine leishmaniasis. New concepts of epidemiology and immunopathology: their i...
Abranches, P; Campino, L; Santos-Gomes, G MVisceral leishmaniasis (VL) is a zoonosis in most regions where it occurs. Dogs are the most important reservoir of the disease and are mainly responsible for the persistence of VL in the Paleartic and Neotropical regions. Canine leishmaniasis (CaL) is a viscerocutaneous, chronic infection with a worse prognosis than human disease. We now know that, as in man, there are some cases of asymptomatic infection. For...
Quality control of the micro-ELISA technic applied to the diagnosis of human an...
Mauricio, I; Campino, L; Abranches, PVisceral leishmaniasis (VL) or kala-azar is, in Portugal, a zoonosis with the dog as reservoir. A quality control of the technique of micro-ELISA was carried out, using as reference the technique of IFI, the most commonly used for the diagnosis of this protozoosis, both for human and canine sera. Three different methods were used to estimate the cut-off point: X + 2sd (average for negative sera plus two standar...
Quality control methods in sero-immunologic tests for infectious diseases.
Abranches, P; Fernandes, J PThe different quality control methods which should be used in seroimmunological assays for detection of antibodies in infectious disease are analyzed. The concepts of reliability, sensitivity, specificity, cut off, efficacy and predictive value are described, explained how they can be calculated and exemplified. The statistics which can be used for comparing results in different situations it is also referred.;...