53 documents found, page 1 of 6

Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer...

Doxorubicin (Dox) is a chemotherapeutic agent widely used in the clinic, whose side effects include cardiotoxicity, associated with decreased antioxidant defenses and increased oxidative stress. The association of Dox with natural antioxidants can extend its use if not interfering with its pharmacological potential. In this study, we aimed to understand the effects and mechanisms of the aqueous extract of Acroc...

Microleakage Study of a Bulk Fill over an Uncured Adhesive System

This study aimed to evaluate and compare the microleakage of composite resin restorations under a total-etch adhesive system applied with two different techniques, with and without cure. Cavities were made on the buccal surface of twenty-six intact teeth and subsequently restored with bulk-fill flow composite resin (SDR®® flow+) and conventional resin (Spectra™ ST HV). Two experimental groups were created, one ...

The Potential Effect of Lidocaine, Ropivacaine, Levobupivacaine and Morphine on...

Breast cancer (BC) is one of the most common types of cancer and the second leading cause of death in women. Local anaesthetics (LAs) and opioids have been shown to influence cancer progression and metastasis formation in several pre-clinical studies. However, their effects do not seem to promote consensus. A systematic review was conducted using the databases Medline (via PubMed), Scopus, and Web of Science (2...

Afinidade: recordando a professora Laura Pires

Afinidade: recordando a professora Laura Pires

From Space to Mental Space: A Cognitive Perspective into Narrative and the Arch...

Spatial metaphors are pervasive across models and theories about the structure and the meaning-making processes of the human mind: metaphorical and metonymic mappings (Lakoff and Johnson 1980, Barcelona 2012), mental spaces (Fauconnier 1994, 1997) or semantic domains (Fauconnier and Sweetser 1996, Brandt 2004) are examples of this spatial ubiquity in cognitive science. In narratology, categories of location and...

Apical Sealing Ability of Two Calcium Silicate-Based Sealers Using a Radioactiv...

The aim of this study was to evaluate and compare the sealing ability of two calcium silicate-based sealers (TotalFill BC RRM Fast Set Putty and White ProRoot MTA) when used as apical plugs in immature teeth through nuclear medicine. Single-rooted extracted teeth (n = 34) had their crowns and root tip sectioned to obtain 14 mm long root segments to simulate an in vitro apexification model. Were created two expe...

Plasmatic Oxidative and Metabonomic Profile of Patients with Different Degrees ...

Acute pancreatitis (AP) is an inflammatory process of the pancreas with variable involvement of the pancreatic and peripancreatic tissues and remote organ systems. The main goal of this study was to evaluate the inflammatory biomarkers, oxidative stress (OS), and plasma metabolome of patients with different degrees of biliary AP severity to improve its prognosis. Twenty-nine patients with biliary AP and 11 heal...

Open-Air Cold Plasma Device Leads to Selective Tumor Cell Cytotoxicity

The need for effective and safe therapies for cancer is growing as aging is modifying its epidemiology. Cold atmospheric plasma (CAP) has gained attention as a potential anti-tumor therapy. CAP is a gas with enough energy to ionize a significant fraction of its constituent particles, forming equal numbers of positive ions and electrons. Timely-resolved output voltage measurement, emission spectroscopy, and quan...

From space to mental space: a cognitive perspective into narrative and the arch...

Spatial metaphors are pervasive across models and theories about the structure and the meaning-making processes of the human mind: metaphorical and metonymic mappings (Lakoff and Johnson 1980, Barcelona 2012), mental spaces (Fauconnier 1994, 1997) or semantic domains (Fauconnier and Sweetser 1996, Brandt 2004) are examples of this spatial ubiquity in cognitive science. In narratology, categories of location and...