4 documents found, page 1 of 1
Antibacterial activity and mode of action of selected glucosinolate hydrolysis ...
Borges, Anabela; Abreu, Ana C.; Ferreira, Carla; Saavedra, Maria J.; Simões, Lúcia C.; Simões, ManuelPlants contain numerous components that are important sources of new bioactive molecules with antimicrobial properties. Isothiocyanates (ITCs) are plant secondary metabolites found in cruciferous vegetables that are arising as promising antimicrobial agents in food industry. The aim of this study was to assess the antibacterial activity of two isothiocyanates (ITCs), allylisothiocyanate (AITC) and 2-phenylethyl...
Antimicrobial activity of selected phytochemicals against Escherichia coli and ...
Monte, J.; Abreu, Ana C.; Borges, Anabela; Simões, Lúcia C.; Simões, M.Bacteria can be resistant to multiple antibiotics and we are fast approaching a time when antibiotics will not work on some bacterial infections. New antimicrobial compounds are urgently necessary. Plants are considered the greatest source to obtain new antimicrobials. This study aimed to assess the antimicrobial activity of four phytochemicals—7-hydroxycoumarin (7-HC), indole-3-carbinol (I3C), salicylic acid (...
Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphyl...
Abreu, Ana C.; Borges, Anabela; Simões, Lúcia C.; Saavedra, Maria J.; Simões, M.The present study has been aimed to assess the antibacterial effects of the glucosinolate hydrolysis product phenyl isothiocyanate (PITC) against Escherichia coli and Staphylococcus aureus. Aspects on the antibacterial mode of action of PITC have also been characterized, such as the changes on surface physicochemical characteristics and membrane damage. The minimum inhibitory concentration of PITC was 1000 µg/m...
Persister cells in a biofilm treated with a biocide
Simões, Lúcia C.; Lemos, Madalena; Pereira, Ana M.; Abreu, Ana C.; Saavedra, Maria J.; Simões, M.This study investigated the physiology and behaviour following treatment with ortho-phthalaldehyde (OPA), of Pseudomonas fluorescens in both the planktonic and sessile states. Steady-state biofilms and planktonic cells were collected from a bioreactor and their extracellular polymeric substances (EPS) were extracted using a method that did not destroy the cells. Cell structure and physiology after EPS extractio...