18 documents found, page 1 of 2
AlergiaPT: A Portuguese media campaign to inspire people with allergies to make...
Moreira, A.; Mendes, F.C.; Rama, T.; Mota, D.; Silva, D; Pádua, I.; Abreu, C; Vasconcelos, MJ; Farraia, M; Paciência, I; Rufo, J; Barros, Renata
Validation of App and Phone Versions of the Control of Allergic Rhinitis and As...
Jácome, C; Pereira, AM; Almeida, R; Amaral, R; Correia, MA; Mendes, S; Vieira-Marques, P; Ferreira, JA; Lopes, I; Gomes, J; Vidal, C; López Freire, S
Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis o...
Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Vieira-Marques, P; Mendes, S; Alves-Correia, M; Ferreira, JA; Lopes, I; Gomes, J; Araújo, L; Couto, MBackground: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support. Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma ...
Dna-based detection of mycobacterium avium subsp. Paratuberculosis in domestic ...
Sousa, T; Costa, M; Sarmento, P; Manso, MC; Abreu, C; Bull, TJ; Cabeda, J; Sarmento, AMycobacterium avium subsp. paratuberculosis (MAP) may play a role in the pathology of human inflammatory bowel disease (IBD). Previously, we found a high frequency (98% in patients with active disease) of MAP DNA detection in the blood of Portuguese Crohn s Disease patients, suggesting this cohort has high exposure to MAP organisms. Water is an important route for MAP dissemination, in this study we therefore a...
Atopic Dermatitis Host and Environment Model: Revisiting Therapeutic Options
Lopes, A; Sokolova, A; Abreu, C; Lopes, CAtopic Dermatitis affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of its triggers and includes emollients, topical steroids and calcineurin inhibitors among others. Immunological dysfunction can be addressed broadly with systemi...
Human rabies: Optimization of prevention and paths towards the cure
Conceição, P; Abreu, CIntroduction: Rabies is one of the oldest and deadliest infectious diseases known by human beings and is commonly transmitted by animal bites. Dogs have a major role in the transmission of the virus. Rabies has no approved curative therapy, and its prevention, even though it is highly effective, it is complex, expensive and challenging in terms of accessibility, particularly regarding immunoglobulin. This revie...
Short and extended provocation tests have similar negative predictive value in ...
Regateiro, FS; Rezende, I; Pinto, N; Abreu, C; Carreiro-Martins, P; Gomes, ERIntroduction and objectives: Drug provocation tests (DPTs) are the gold-standard method to diagnose non-immediate hypersensitivity reactions (NIHSR) to beta-lactam antibiotics (BL) in children. Our aim was to compare the negative predictive value (NPV) of one-day (short) DPT versus 3-7 days (extended) DPT for the diagnosis of NIHSR to BL in paediatric age. A secondary aim was to compare confidence on drug re-ex...
Short and Extended Provocation Tests Have Similar Negative Predictive Value in ...
Regateiro, FS; Rezende, I; Pinto, N; Abreu, C; Carreiro-Martins, P; Gomes, ERDrug provocation tests (DPTs) are the gold-standard method to diagnose non-immediate hypersensitivity reactions (NIHSR) to beta-lactam antibiotics (BL) in children. Our aim was to compare the negative predictive value (NPV) of one-day (short) DPT versus 3-7 days (extended) DPT for the diagnosis of NIHSR to BL in paediatric age. A secondary aim was to compare confidence on drug re-exposure after short and extend...
Mononeuritis multiplex: an uncommon neurological manifestation of cytomegalovir...
Palma, P; Costa, A; Duro, R; Neves, N; Abreu, C; Sarmento, ABACKGROUND: Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifestations include encephalitis, myelitis, polyradiculopathy and, less commonly, mononeuritis multiplex (MNM). We report a case of disseminated CMV disease with gastrointestinal and peripheral and ...
Emerging biosensing technologies for neuroinflammatory and neurodegenerative di...
Abreu, C; Soares-Dos-Reis, R; Melo, PN; Relvas, JB; Guimarães, J; Sá, M; Cruz, AP; Pinto, INeuroinflammation plays a critical role in the onset and progression of many neurological disorders, including Multiple Sclerosis, Alzheimer’s and Parkinson’s diseases. In these clinical conditions the underlying neuroinflammatory processes are significantly heterogeneous. Nevertheless, a common link is the chronic activation of innate immune responses and imbalanced secretion of pro and anti-inflammatory media...