2 documents found, page 1 of 1
Is the proteome of bronchoalveolar lavage extracellular vesicles a marker of ad...
Carvalho, AS; Moraes, MCS; Na, CH; Fierro-Monti, I; Henriques, A; Zahedi, S; Bodo, C; Tranfield, EM; Sousa, AL; Farinho, A; Rodrigues, LV; Pinto, PAcellular bronchoalveolar lavage (BAL) proteomics can partially separate lung cancer from non-lung cancer patients based on principal component analysis and multivariate analysis. Furthermore, the variance in the proteomics data sets is correlated mainly with lung cancer status and, to a lesser extent, smoking status and gender. Despite these advances BAL small and large extracellular vehicles (EVs) proteomes r...
Profiling of lung microbiota discloses differences in adenocarcinoma and squamo...
Gomes, S; Cavadas, B; Ferreira, JC; Marques, PI; Monteiro, C; Sucena, M; Sousa, C; Rodrigues, LV; Teixeira, G; Pinto, P; Abreu, TT; Bárbara, CThe lung is a complex ecosystem of host cells and microbes often disrupted in pathological conditions. Although bacteria have been hypothesized as agents of carcinogenesis, little is known about microbiota profile of the most prevalent cancer subtypes: adenocarcinoma (ADC) and squamous cell carcinoma (SCC). To characterize lung cancer (LC) microbiota a first a screening was performed through a pooled sequencing...