This study aimed at evaluating the antidepressant-like action of the marine alga Solieria filiformis lectin (SfL) and to investigate the participation of the monoaminergic system in this action. For this, male Swiss mice (n=10) were pretreated with intravenous injections (i.v.) of SfL (1, 3 or 9mg/kg) and submitted to open field (OFT), tail suspension (TST), forced swimming (FST), elevated plus-maze (EPMT) and ...
The seaweeds are a source of bioactive compounds, which gained importance in pharmacological applications. Among these, there are the lectins, which are (glyco)proteins that bind to specific mono or oligosaccharides. The aim of this study was to isolate the lectin from the red seaweed Solieria filifmoris (LSf), investigate its properties in acute nociception and inflammation, and their possible signs of toxicit...
ABREU, Ticiana Monteiro. Lectina da alga marinha vermelha Solieria filiformis (Kützing) P.W. Gabrielson: caracterização parcial e efeito antidepressivo em modelos experimentais de depressão. 2016. 132 f. Tese (Doutorado em Bioquímica)-Universidade Federal do Ceará, Fortaleza-CE, 2016.; Lectins are proteins that bind to specific mono or oligosaccharides. This interaction with carbohydrates makes of the lectins v...