3 documents found, page 1 of 1
New CTX-M group conferring β-Lactam resistance: A compendium of phylogenetic in...
Mendonça, Jacinta; Guedes, Carla; Silva, Carina; Sá, Sara; Oliveira, Marco; Accioly, Gustavo; Baylina, Pilar; Barata, Pedro; Pereira, CláudiaThe production of extended-spectrum β-lactamases (ESBLs) is the main defense mechanism found in Gram negative bacteria. Among all the ESBLs, the CTX-M enzymes appear as the most efficient in terms of dissemination in different epidemiological contexts. CTX-M enzymes exhibit a striking plasticity, with a large number of allelic variants distributed in several sublineages, which can be associated with functional ...
Effect of umbilical cord mesenchymal stem cells secretome in melanoma
Accioly, Gustavo; Aguiar, Gonçalo; Areal, Lara; Costa, Pedro; Coelho, Pedro; Gomes, AndreiaMelanoma of the skin is one of the most prominent and fastest growing malignancies. More than 300 thousand diagnosed cases and 57 thousand deaths in 2020 worldwide and roughly 517 thousand cases of were registered during the 2015-2020 period. Melanoma is generally regarded as an aggressive and unpredictable cancer whose conventional therapies, such as local excision, chemotherapy and immunotherapy, have encount...
New CTX‐M group conferring β‐lactam resistance: a compendium of phylogenetic in...
Mendonça, Jacinta; Guedes, Carla; Silva, Carina; Sá, Sara; Oliveira, Marco; Accioly, Gustavo; Baylina, Pilar; Barata, Pedro; Pereira, CláudiaThe production of extended‐spectrum β‐lactamases (ESBLs) is the main defense mechanism found in Gram negative bacteria. Among all the ESBLs, the CTX‐M enzymes appear as the most efficient in terms of dissemination in different epidemiological contexts. CTX‐M enzymes exhibit a striking plas-ticity, with a large number of allelic variants distributed in several sublineages, which can be associated with functional...