10 documents found, page 1 of 1
PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated ...
Munari, Fernanda Franco; Cruvinel-Carloni, Adriana; Lacerda, Croider Franco; De Oliveira, Antônio Talvane Torres; Scapulatempo-Neto, CristovamMade available in DSpace on 2019-10-06T16:11:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-29; Background: Chronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are poorly understood. Objective: We analyzed hotspot PIK3CA gene mutations in a series...
Clinical and anatomopathological aspects of patients with hantavirus cardiopulm...
Santos, João Paulo Vieira dos; Adad, Sheila Jorge; Vergara, Mário-León Silva; Micheletti, Adilha Misson RuaThe hantavirus cardiopulmonary syndrome is considered an emerging disease in the Americas. Since 1993, thousands of cases have been reported from different countries, but mainly from Brazil. This study aims to describe some epidemiological, clinical and anatomopathological aspects of patients with hantavirus who presented poor outcome and were autopsied in a teaching hospital in Brazil, from 2000 to 2014. Of th...
Main findings and diagnostic yield of bronchoalveolar lavage, bronchial brushin...
Santos, João Paulo Vieira dos; Leite, Lucas Fabiano Garcia; Adad, Sheila Jorge; Vergara, Mário-León Silva; Micheletti, Adilha Misson RuaHIVBronchoalveolar lavage, bronchial brushing and transbronchial biopsy are of fundamental importance in the diagnosis of pathologies affecting the lungs of immunosuppressed patients, especially those infected with HIV. This was a descriptive and retrospective study, in which the results of bronchoalveolar lavages, bronchial brushings and transbronchial biopsies of HIV-positive patients attended at the Clinical...
PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated ...
Munari, Fernanda Franco; Cruvinel-Carloni, Adriana; Lacerda, Croider Franco; de Oliveira, Antônio Talvane Torres; Scapulatempo-Neto, CristovamChronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are poorly understood.
Morphological changes in the digestive system of 322 necropsies of patients wit...
Guimarães, Lucinda Calheiros; Silva, Ana Cristina Araújo Lemos da; Micheletti, Adilha Misson Rua; Moura, Everton Nunes Melo; Silva-Vergara, Mario LéonInvolvement of the digestive system in AIDS pathologies or injuries is frequent. Aiming at comparing the frequency, the importance that these lesions have for death and the survival time in patients using or not using HAART, we studied 322 necropsies classified as follows: Group A - without antiretroviral drugs (185 cases); B - one or two antiretroviral drugs or HAART for less than six months (83 cases); C - HA...
Vasos sanguíneos em gânglios no esôfago humano poderiam explicar a maior freqüê...
Adad, Sheila Jorge; Etchebehere, Renata Margarida; Jammal, Alessandro AdadEste estudo teve como objetivo avaliar se existem ou não vasos sanguíneos no interior de gânglios do plexo mientérico do esôfago e cólon humano. Foram examinados 15 casos de necrópsias de natimortos, recém-nascidos e crianças de até dois anos de idade, sem alterações gastrintestinais, que faleceram por doenças em outros órgãos. Foram analisados anéis do esôfago e cólon, fixados em formol e processados para incl...
Human papillomavirus types 16 and 18 and the prognosis of patients with stage I...
Zampronha, Rossana de Araújo Catão; Freitas-Junior, Ruffo; Murta, Eddie Fernando Candido; Michelin, Márcia Antoniazi; Barbaresco, Aline AlmeidaOBJECTIVE: This study sought to evaluate the prevalence of human papillomavirus (HPV) types 16 and 18 in women with clinical stage IB cervical cancer treated by radical hysterectomy with pelvic lymphadenectomy as well as to establish a correlation between HPV type and cancer prognosis. METHODS: A single-center cohort study was conducted with 86 patients who had undergone radical hysterectomy for stage I cervica...
Morphological changes in the digestive system of 93 human immunodeficiency viru...
Guimarães, Lucinda Calheiros; Silva, Ana Cristina Araujo Lemos; Micheletti, Adilha Misson Rua; Moura, Everton Nunes Melo; Silva-Vergara, Mario LeonInvolvement of the digestive system in patients with acquired immunodeficiency syndrome (AIDS) is frequent and many changes in these patients are diagnosed only at autopsy. There are few studies of autopsy with detailed analysis of this system and only one was conducted in Brazil. We evaluated each segment of the digestive system in 93 consecutive autopsies of patients infected with human immunodeficiency virus...
Benign and malignant neoplasias in 261 necropsies for HIV-positive patients in ...
Micheletti, Adilha Rua; Macedo, Ana Carolina Sandoval; Silva, Gisele Barbosa e; Silva, Ana Cristina Araújo Lemos da; Silva-Vergara, Mário LeonConsidering that there are some studies with autopsies from AIDS describing only malignant neoplasias and that changes can occur after the introduction of Highly Active Antiretroviral Therapy (HAART), our objectives were to analyze the frequency of benign and malignant neoplasms in AIDS patients in the periods of both pre- and post-HAART. This is a retrospective study with 261 autopsies of HIV-positive patients...
Local lymphocytes and nitric oxide synthase in the uterine cervical stroma of p...
Silva, Cléber Sergio da; Michelin, Marcia Antoniazi; Etchebehere, Renata Margarida; Adad, Sheila Jorge; Murta, Eddie Fernando CandidoOBJECTIVES: Precancerous and cancerous cells can trigger an immune response that may limit tumor development and can be used as a prognostic marker. The aims of the present study were to quantify the presence of B and T lymphocytes, macrophages and cells expressing inducible nitric oxide synthase (iNOS) in the cervical stroma of women with grade III cervical intraepithelial neoplasia (CIN III) or in the intratu...