7 documents found, page 1 of 1
Impact of Preoperative Chemotherapy Features on Patient Outcomes after Hepatect...
Innominato, P; Cailliez, V; Allard, MA; Lopez-Ben, S; Ferrero, A; Pinto Marques, H; Hubert, C; Giuliante, F; Pereira, F; Cugat, E; Mirza, DBackground: Prognostic factors have been extensively reported after resection of colorectal liver metastases (CLM); however, specific analyses of the impact of preoperative systemic anticancer therapy (PO-SACT) features on outcomes is lacking. Methods: For this real-world evidence study, we used prospectively collected data within the international surgical LiverMetSurvey database from all patients with initial...
Graft Protection Against Cold Ischemia Preservation: An Institute George Lopez ...
Panisello-Rosello, A; Castro-Benítez, C; Lopez, A; Balloji, S; Folch-Puy, E; Adam, R; Roselló-Catafau, JCold storage of organs in preservation solutions, such as Institute George Lopez 1 (IGL-1) or histidine-tryptophan-ketoglutarate (HTK), is a mandatory step for organ transplantation. This preservation leads to an ischemic injury that affects the outcome of the organ. This article studies the liver graft eluate after organ recovery using IGL-1 or HTK solutions. We explore the influence of the volume used for was...
Liver transplantation for colorectal liver metastasis: Survival without recurre...
Toso, C; Pinto Marques, H; Andres, A; Castro e Sousa, F; Adam, R; Kalil, A; Clavien, PA; Furtado, E; Barroso, E; Bismuth, H
Resection of Colorectal Liver Metastases After Second-Line Chemotherapy: Is It ...
Adam, R; Yi, B; Innominato, PF; Barroso, E; Laurent, C; Giuliante, F; Capussotti, L; Lapointe, R; Regimbeau, JM; Lopez-Ben, S; Isoniemi, H; Hubert, CPURPOSE: Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line. PATIENTS AND METHODS: From January 2005 to June 2013, 5624 and 791 consecutive patients of a prospective international cohort received ...
Outcomes of Parenchyma-Preserving Hepatectomy and Right Hepatectomy for Solitar...
Hosokawa, I; Allard, MA; Mirza, DF; Kaiser, G; Barroso, E; Lapointe, R; Laurent, C; Ferrero, A; Miyazaki, M; Adam, RBACKGROUND: Occasionally, right hepatectomy, rather than parenchyma-preserving hepatectomy, has been performed for solitary small colorectal liver metastasis. The relative oncologic benefits of parenchyma-preserving hepatectomy and right hepatectomy are unclear. This study compared the outcomes of patients with solitary small colorectal liver metastasis in the right liver who underwent parenchyma-preserving hep...
Conversion to resection of liver metastases from colorectal cancer with hepatic...
Lévi, FA; Boige, V; Hebbar, M; Smith, D; Lepère, C; Focan, C; Karaboué, A; Guimbaud, R; Carvalho, C; Tumolo, S; Innominato, P; Ajavon, Y; Truant, SBACKGROUND: Systemic chemotherapy typically converts previously unresectable liver metastases (LM) from colorectal cancer to curative intent resection in ∼15% of patients. This European multicenter phase II trial tested whether hepatic artery infusion (HAI) with triplet chemotherapy and systemic cetuximab could increase this rate to 30% in previously treated patients. PATIENTS AND METHODS: Participants had unre...
ESMO consensus guidelines for the management of patients with metastatic colore...
Van Cutsem, E; Cervantes, A; Adam, R; Sobrero, A; Van Krieken, J H; Aderka, D; Aranda Aguilar, E; Bardelli, A; Benson, A; Bodoky, G; Ciardiello, FColorectal cancer (CRC) is one of the most common malignancies in Western countries. Over the last 20 years, and the last decade in particular, the clinical outcome for patients with metastatic CRC (mCRC) has improved greatly due not only to an increase in the number of patients being referred for and undergoing surgical resection of their localised metastatic disease but also to a more strategic approach to th...