3 documents found, page 1 of 1
Monitoring of the forgotten immune system during critical illness: a narrative ...
Adao-Serrano, Maria; Gomes, André; Fernandes, Susana M.Immune organ failure is frequent in critical illness independent of its cause and has been acknowledged for a long time. Most patients admitted to the ICU, whether featuring infection, trauma, or other tissue injury, have high levels of alarmins expression in tissues or systemically which then activate innate and adaptive responses. Although necessary, this response is frequently maladaptive and leads to organ ...
Future without delirium: not quite there yet but we can start by prescribing touch
Fernandes, Susana M.; Adao-Serrano, Maria; Rodrigues, Ana Rita; Belo, PatríciaThe recently published article by Kotfs et al. “The future of intensive care: delirium should no longer be an issue”, brought us great interest and although we agree with the authors’ perspective this is still far from being reality. Despite delirium increase report as an adverse event, it is often faced on daily practice as a patient’s “weakness” or an inevitability due to acute illness that we fail to avoid. ...
SARS‐CoV2 pneumonia recovery is linked to expansion of innate lymphoid cells ty...
Gomes, André; Farias, Guilherme B.; Dias Silva, Manuel; Laia, Joel; Trombetta, Amelia Chiara; Godinho-Santos, Ana; Rosmaninho, Pedro; Santos, Diana F.Accelerate lung repair in SARS-CoV-2 pneumonia is essential for pandemic handling. Innate lymphoid cells (ILCs) are likely players, given their role in mucosal protection and tissue homeostasis. We studied ILC subpopulations at two time points in a cohort of patients admitted in the hospital due to SARS-CoV-2 infection. COVID-19 patients with moderate/severe respiratory failure featured profound depletion of ci...