8 documents found, page 1 of 1
Abnormal p53 High-Grade Endometrioid Endometrial Cancer
Casanova, Joao; Babiciu, Alexandru-romualdo; Duarte, Gonçalo S; da Costa, Ana Gomes; Silvério Serra, Sofia; Costa, Teresa; Catarino, AnaPublisher Copyright: © 2024 by the authors.; Objective: Our primary objective was to evaluate the oncologic outcomes of patients with abnormal p53 FIGO grade 3 (high-grade) endometrioid endometrial cancer. As secondary objectives, we determined the global prevalence of abnormal p53 in grade 3 endometrioid endometrial carcinomas and the geographical variations. Methods: The following electronic databases were se...
Case Report
Tripepi, Marta; da Costa, Ana G.; Albergaria, Diogo; Costa, Andreia; Catarino, Ana; Duarte, Ana Luisa; Bartosch, Carla; Schuler, VeronicaPublisher Copyright: Copyright © 2025 Tripepi, da Costa, Albergaria, Costa, Catarino, Duarte, Bartosch, Schuler, Oliveira, Lima and Casanova.; Small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a rare, highly aggressive malignancy that predominantly affects young women. We report a 32-year-old pregnant woman diagnosed with SCCOHT during the first trimester of pregnancy. At 24 weeks, imaging reve...
Prognosis of polymerase epsilon (POLE) mutation in high-grade endometrioid endo...
Casanova, Joao; Duarte, Gonçalo Silva; da Costa, Ana Gomes; Catarino, Ana; Nave, Mónica; Antunes, Telma; Silvério Serra, Sofia; Dias, Sara SimõesFunding Information: This work in the context of the “Women's Health and Maternal Fetal Research Group” was partially co-financed by Hospital da Luz Lisboa under the initiative “Luz Investigação”. Dr. Abu-Rustum was supported in part by a National Cancer Institute/National Institutes of Health Cancer Center Support Grant ( P30 CA008748 ). The funding sources were not involved in study design; collection, analys...
Molecular classification of endometrial cancer
Casanova, João; da Costa, Ana G.; Lopes, Ana Pestana; Catarino, Ana; Nave, Mónica; Sousa, Ana Carla; Lima, JorgePublisher Copyright: Copyright © 2024 Casanova, da Costa, Lopes, Catarino, Nave, Sousa and Lima.; Background: Since the seminal publication of the TCGA consortium in 2013, the molecular classification of endometrial cancer has been widely accepted as a new and powerful tool to better understand the natural history of this malignancy. Adoption of routine molecular classification around the world has been limited...
The PALliative MUlticenter Study in Intensive Care (PalMuSIC). Results From a M...
Correia, Iuri; Simas, Ângela; Chaves, Susana; Paixão, Ana Isabel; Catarino, Ana; Gonçalves-Pereira, JoãoPublisher Copyright: © The Author(s) 2021.; Introduction: Frailty is a clinically recognizable state of increased vulnerability common in critical medicine. When underrecognized, it may lead to invasive treatments that do not serve the patients’ best interest. Our aim was to evaluate the use of both palliative care consultation and invasive interventions in frail patients admitted to Intensive Care Units in Por...
COVID-19 symptoms at hospital admission vary with age and sex
Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent; Absil, Lara; Acker, Andrew; Adachi, Shingo; Adam, Elisabeth; Adriao, Diana; Ainscough, KateFunding This work was supported by the Department for International Development and Wellcome Trust [215091/Z/18/Z]; the Bill and Melinda Gates Foundation [OPP1209135]. Country-specifc support was provided by the Canadian Institutes of Health Research Coronavirus Rapid Research Funding Opportunity [OV2170359]; the Health Research Board Ireland [CTN Award 2014-012]; National Institute for Health Research (NIHR) [...
Antibody response to Phlebotomus perniciosus saliva in cats naturally exposed t...
Pereira, André; Cristóvão, José Manuel; Vilhena, Hugo; Martins, Ângela; Cachola, Patrícia; Henriques, Joaquim; Coimbra, Mónica; Catarino, AnaBACKGROUND: Zoonotic leishmaniosis, caused by the protozoan Leishmania infantum, is a public and animal health problem in Asia, Central and South America, the Middle East and the Mediterranean Basin. Several phlebotomine sand fly species from the subgenus Larroussius are vectors of L. infantum. Data from dogs living in endemic areas of leishmaniosis advocate the use of antibody response to phlebotomine sand fly...
Bilateral breast fibromatosis after silicone prosthetics in a patient with clas...
Silva, Sara; Lage, Pedro; Cabral, Francisco; Alves, Rui; Catarino, Ana; Félix, Ana; André, SaudadeBreast fibromatosis is a benign fibroblastic proliferation accounting for less than 0.2% of breast tumors. It presents sporadically or as a manifestation of familial adenomatous polyposis (FAP). Fibromatosis in FAP may develop in patients with adenomatous polyposis coli (APC) gene mutations at any location through the gene. Notably, there is an increased risk if mutation is downstream codon 1400. The present ca...