6 documents found, page 1 of 1
Kinetics of torque teno virus viral load is associated with infection and de no...
Querido, Sara; Martins, Catarina; Gomes, Perpétua; Pessanha, Maria Ana; Arroz, Maria Jorge; Adragão, Teresa; Casqueiro, Ana; Oliveira, ReginaTorque teno virus (TTV) was recently identified as a potential biomarker for the degree of immunosuppression, and potentially as a predictor of rejection and infection in solid organ transplant patients. We evaluated TTV viral load in kidney transplant (KT) patients during the first year post-transplant to examine overall kinetics and their relationships with deleterious events, including episodes of infection ...
Detection of JCV or BKV viruria and viremia after kidney transplantation is not...
Querido, Sara; Weigert, Andre; Pinto, Iola; Papoila, Ana Luísa; Pessanha, Maria Ana; Gomes, Perpétua; Adragão, Teresa; Paixão, PauloStudies analyzing the relationship between BK polyomavirus (BKV) or JC polyomavirus (JCV) infection and kidney transplant (KT) long term clinical outcomes are scarce. Therefore, we evaluated this relationship in a single-center retrospective cohort of 288 KT patients followed for 45.4(27.5; 62.5) months. Detection of BKV viremia in two consecutive analyses led to discontinuation of antimetabolite and initiation...
Outcomes of living kidney donor candidates and living kidney recipient candidat...
Querido, Sara; Ormonde, Carolina; Adragão, Teresa; Costa, Inês; Pessanha, Maria Ana; Gomes, Perpétua; Weigert, AndréIntroduction. Recent data have emerged about a protective association between JCV viruria and chronic kidney disease (CKD). Material and Methods. Single-center retrospective cohort study; 230 living kidney donors (LKD) candidates and 59 potential living kidney receptors (LKR) were enrolled. Plasma and urinary JCV and BKV viral loads were measured in all LKD candidates and in nonanuric LKR candidates. Twenty-six...
High‐grade urothelial carcinoma in a kidney transplant recipient after JC virus...
Querido, Sara; Fernandes, Isabel; Weigert, Andre; Casimiro, Sandra; Albuquerque, Catarina; Ramos, Sância; Adragão, Teresa; Luz, Ivan; Paixão, PauloKidney transplant (KT) recipients have an increased risk for urothelial carcinoma. A role for JC virus (JCV) in human cancers is not yet proved but there is an increasingly reported association between BK virus (BKV) nephropathy and renourinary neoplasms. We report a KT recipient who developed a high-grade urothelial carcinoma 5 years after a diagnosis of JCV nephropathy and 9 years after kidney transplantation...
Rewards to increase living kidney donation: the state of the art
Querido, Sara; Weigert, Andre; Adragão, Teresa; Machado, Domingos; Pais, DiogoThe incidence of end-stage renal disease (ESRD) is increasing worldwide. When compared to dialysis, renal transplantation (RT) leads to a survival advantage and to an improvement in quality of life in most ESRD patients. Additionally, from a societal perspective, RT is the most cost-effective modality of renal replacement therapy (RRT) for eligible patients. In the last decades, RT has prolonged and improved th...
A plain X-ray vascular calcification score is associated with arterial stiffnes...
Adragão, Teresa; Pires, Ana; Birne, Rita; Curto, José Dias; Lucas, Carlos; Gonçalves, Margarida; Negrão, Acácio PitaBackground. Vascular calcifications are highly prevalent in dialysis patients and are associated with arterial stiffness and mortality. The use of simple and inexpensive methods to evaluate arterial stiffness and vascular calcifications is desired. The objective of this study was to evaluate the relationship of a simple vascular calcification score (SVCS) with pulse wave velocity (PWV) and pulse pressure (PP) a...