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Characterisation of peptide-based inhibitors to tackle Triple-Negative Breast C...

Afonso, Alexandra

Abstract Breast cancer (BC) is the second most diagnosed cancer globally and the leading cause of cancer-related mortality among women. Triple-negative breast cancer (TNBC), the most aggressive subtype, is characterized by a high metastatic potential, treatment resistance, and increased recurrence rates, highlighting the need for effective therapeutic strategies. The Frizzled 7 (FZD7) receptor, associated with ...


Ecotoxicological risk assessment as a decision tool for the valorisation of win...

Luz, Silvana; Catarino, Adriana; Rivas, Javier; Carvalho, Fátima; Palma, Patrícia; Santos, Maria Teresa; Afonso, Alexandra; Regato, Mariana

A simple and economical process consisting in the precipitation with slaked lime (Ca(OH)2) was applied to winery wastewater. The process not only removed organic matter and other contaminants but also simultaneously captured atmospheric CO2. In order to help the wine industry to advance to the objective of circular economy, treatment byproducts (supernatant and sludge) have been reused for agricultural purposes...


Pretreated Agro-Industrial Effluents as a Source of Nutrients for Tomatoes Grow...

Correia, Tânia; Correia, Pedro; Fernandes, Annabel; Carvalho, Maria João; Afonso, Alexandra; Ribeiro, Carlos; Regato, Mariana; Costa, Idália

In a zero-waste approach for the agro-industrial sector, this study aimed to evaluate the reuse of cheese whey wastewater (chemical oxygen demand = 2.1 g L−1) pretreated by immediate one-step lime precipitation followed by natural carbonation as a nutritive solution for tomato production in hydroponic systems. Pretreated effluent, diluted with groundwater (1:6) and supplemented with nutrients, was utilized to i...


Pretreated Agro-Industrial Effluents as a Source of Nutrients for Tomatoes Grow...

Afonso, Alexandra; Ribeiro, Carlos; Carvalho, Maria João; Correia, Tânia; Correia, Pedro; Regato, Mariana; Costa, Idália; Fernandes, Annabel

In a zero-waste approach for the agro-industrial sector, this study aimed to evaluate the reuse of cheese whey wastewater (chemical oxygen demand = 2.1 g L−1) pretreated by immediate one-step lime precipitation followed by natural carbonation as a nutritive solution for tomato production in hydroponic systems. Pretreated effluent, diluted with groundwater (1:6) and supplemented with nutrients, was utilized to i...

Date: 2023   |   Origin: uBibliorum

Reuse of Pretreated Agro-Industrial Wastewaters for Hydroponic Production of Le...

Afonso, Alexandra; Regato, Mariana; Patanita, Mariana; Luz, Silvana; Carvalho, Maria João; Fernandes, Annabel; Lopes, Ana; Almeida, Adelaide

The utilization of agro-industrial wastewaters (AIWWs), pretreated by immediate one-step lime precipitation + natural carbonation, as a nutritive solution for the hydroponic production of lettuce was evaluated. The AIWWs studied were olive mill wastewater (OMW), winery wastewater (WW), and cheese whey wastewater (CWW). Lettuces (Lactuca sativa L. var. crispa) were grown in a closed nutrient film technique hydro...

Date: 2023   |   Origin: uBibliorum

Landfill leachate treatment by immediate one-step lime precipitation, carbonati...

Ramalho, Mário; Jovanović, Toni; Baía, Ana; Lopes, Ana; Fernandes, Annabel; Almeida, Adelaide; Carvalho, Fátima; Afonso, Alexandra

The high pollutant load of sanitary landfill leachates poses a huge challenge in the search for efficient and environment friendly solutions for their treatment. The objective of this work was to study an integrated solution of environmentally friendly technologies - immediate one-step lime precipitation (IOSLP), carbonation (CB), and phytoremediation (Phyt) - to treat a sanitary landfill leachate. In the leach...


Immediate one-step lime precipitation process for the valorization of winery wa...

Luz, Silvana; Rivas, Javier; Afonso, Alexandra; Carvalho, Fátima

The winery wastewater (WW) of the Village of Vidigueira, in south of Portugal, presented an acid pH (4.26 ± 0.029), a high content of chemical oxygen demand (COD = 3236 ± 30.43 mg L-1), turbidity (160.0 ± 7.68 NTU), total P (155.5 ± 6.36 mg L-1) K (100.5 mg L-1), and low level of metals: Pb, Cd, Cu, Ni, Mn, Fe, Zn. The K and the total P content could make them attractive from an agricultural point of view. Howe...


Process of treatment of agroindustrial waste water by reaction of acidification...

Prazeres, Ana; Luz, Silvana; Guerreiro, Raquel; Madeira, Luis; Alves, Eliana; Carvalho, Fátima; Afonso, Alexandra; Almeida, Adelaide

The present Invention relates to a process for the treatment from agroindustrial facilities in particular from slaughterhouses, olive oil process, cheese industries or wine producing facilities by reaction of acidification with the addition of strong acids under agitation conditions and precipitation, according to claim 1. The application of this process to agroindustrial wastewater reduces its level of contami...


Desenvolvimento de processos físico-químicos de precipitação e oxidação para tr...

Afonso, Alexandra

A gestão dos efluentes provenientes da produção de azeite tem sido conduzida por aplicação de diversos tratamentos físico-químicos e biológicos, bem como a utilização no solo. No entanto, o mecanismo mais utilizado continua a ser o armazenamento em lagoas e a evaporação natural nos períodos mais quentes do ano. Este trabalho consistiu na caracterização das águas residuais de um lagar de sistema contínuo de duas...


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