Background: The increased focus on quality indicators (QIs) and the use of clinical registries in real-world cancer studies have increased compliance with therapeutic standards and patient survival. The European Society of Breast Cancer Specialists (EUSOMA) established QIs to assess compliance with current standards in breast cancer care. Methods: This retrospective study is part of H360 Health Analysis and aim...
The overexpression of the human epidermal growth factor receptor type 2 (HER2) is present in 20% of all breast cancers and has known prognostic value, associated with a higher risk of recurrence and mortality. Management of these patients has evolved significantly in recent years due to advances in the identification of biomarkers and in treatment efficacy. This article reviews key aspects of the neoadjuvant an...
Introduction: Cancer care providers have faced many challenges in delivering safe care for patients during the COVID-19 pandemic. This cross-sectional survey-based study investigated the impact of the pandemic on clinical practices of Portuguese medical oncologists caring for patients with breast cancer. Methods: An anonymous online survey comprising 42 questions gathered information regarding COVID-19 testing,...
We aimed to characterize the relation between the disease and treatment of cancer with fertility issues.It was applied a specific questionnaire to premenopausal patients with breast cancer. Based in our findings the importance of fertility is greatest for younger and/or still childless patients. The discussion about fertility is more frequent in earlier stages ofcancer and younger patients, but globally occurs ...
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Introduction: This study aimed at evaluating the overall survival (OS) gain associated with human epidermal growth factor receptor 2 (HER2)-directed therapies in patients with metastatic breast cancer (mBC). Methods: A bibliographic search was conducted in PubMed and Cochrane databases. Only phase III randomized controlled trials (RCTs) including HER2-positive (HER2+) mBC patients were included in this review. ...
Oncologic disease is one of the main causes of death in Portugal, as well as a high morbidity rate. Over the past few years, these diseases have been targeted with several strategies which aims at optimizing the use of available therapeutic and diagnostic options. Nevertheless, the amount of quantitative information available regarding the disease, patient profile, and treatment and monitoring practices is very...