147 documents found, page 1 of 15
Longitudinal dynamics of humoral immunity among health care workers in Portugal...
Saraiva, Ana Leonor; Afreixo, Vera; Machado, Ausenda; Gaio, VâniaIntroduction: The emergence of COVID-19 in 2019 led to the rapid development of vaccines and diagnostic tests. To assess antibody responses in healthcare workers (HCWs), a 2021–2022 cohort study was conducted across three Portuguese hospitals. Antibody levels were measured at six intervals: pre-vaccination, post-first dose, at 3, 6, and 12 months after the second dose, and post-booster. Each hospital utilized a...
Linear Regression Analysis of Harmonized IgG Antibody Levels Against the SARS-C...
Saraiva, Ana Leonor; Afreixo, Vera; Machado, Ausenda; Gaio, VâniaThe emergence of COVID-19 in 2019 led to the rapid development of vaccines and diagnostic tests. To assess antibody responses in healthcare workers (HCWs), a cohort study was conducted between 2021 and 2022 across three Portuguese hospitals. Antibody levels were measured at six time points: prevaccination, post-vaccination, and at 3, 6, and 12 months after the vaccination, as well as after the booster dose. Eac...
Development and Application of a Harmonization Method for IgG Antibody Levels A...
Saraiva, Ana Leonor; Afreixo, Vera; Gaio, Vânia; Machado, AusendaIntroduction: The emergence of COVID-19 led to the rapid development of vaccines and diagnostic tests. To assess antibody responses in healthcare workers (HCWs), a 2021–2022 cohort study was conducted in three Portuguese hospitals. Antibody levels were measured at six time points: pre-vaccination, post-first dose, at 3, 6, 12 months after the second dose, and post-booster. Each hospital utilized a different ass...
Effectiveness of specific scapular therapeutic exercises in patients with shoul...
Melo, Ana; Moreira, Juliana; Afreixo, Vera; Gonçalves, Daniel Moreira; Donato, Helena; Cruz, Eduardo B.; Vilas-Boas, J. Paulo; Sousa, AndreiaTherapeutic exercise has been considered a useful tool to rehabilitate shoulder pain, namely through its influence on scapular dynamics. Accordingly, the effectiveness of scapular therapeutic exercise needs to be explored. The present study aims to evaluate the effectiveness of scapular therapeutic exercises in shoulder pain and to identify the most effective exercise type (focal or multijoint) and ways of deli...
Polypharmacy and drug interactions in older patients with cancer receiving chem...
Ferraz Oliveira, Rita; Oliveira, Ana Isabel; Cruz, Agostinho; Ribeiro, Oscar; Afreixo, Vera; Pimentel, FranciscoPolypharmacy in older adults with cancer receiving chemotherapy leads to increased risks of drug interactions, translating in potential hazardous health outcomes. This study aims to assess the prevalence of polypharmacy, drug–drug interactions (DDIs), and severe-drug interactions (SDIs) in older patients with cancer. Antineoplastic agents (ANAs) involvement and possible risk contexts (comorbidities with cardiac...
Complexity of the therapeutic regimen in older adults with cancer: associated f...
Oliveira, Rita F.; Oliveira, Ana I.; Cruz. Agostinho; Ribeiro, Oscar; Afreixo, Vera; Pimentel, Francisco; Cruz, Agostinho; Ferraz Oliveira, RitaPopulation aging is a worldwide phenomenon and is often associated with multimorbidity and polypharmacy. Complex medication regimens are common among older adults and contribute to the occurrence of harmful health outcomes. Age is one of the main risk factors for cancer. This study aimed to determine and characterize the therapeutic complexity in older patients with cancer, and analyze the factors associated wi...
Impacto da COVID-19 na incidência de hospitalizações por lesões autoinfligidas ...
Cardoso, Catarina; Silva, Susana; Alves, Tatiana; Nunes, Baltazar; Afreixo, VeraCom o início da pandemia de COVID-19, a realidade até então conhecida mudou para muitas pessoas. A falta de convivência com familiares e amigos, insegurança, ansiedade, medo de contrair a infeção, problemas económicos decorrentes da pandemia e luto pelos familiares e amigos que perderam e dos quais não se puderam despedir devido às restrições, podem aumentar os riscos para a saúde mental e consequentemente para...
Acute kidney injury after endovascular therapy in acute stroke patients: system...
Oliveira, Marta; Rocha, Ana; Barbosa, Flávia; Barros, Pedro; Almeida, Luísa; Ribeiro, Manuel; Afreixo, Vera; Gregório, TiagoAims Endovascular therapy (EVT) is a highly effective stroke treatment, but it requires the administration of contrast media which puts patients at risk of acute kidney injury (AKI). AKI is associated with increased morbidity and mortality in cardiovascular patients. Methods PubMed, Scopus, ISI and the Cochrane Library were systematically searched for observational and experimental studies assessing the occurre...
Effects of a physical exercise program on quality of life and physical fitness ...
Joaquim, Ana; Amarelo, Anabela; Antunes, Pedro; Garcia, Catarina; Leão, Inês; Vilela, Eduardo; Teixeira, Madalena; Duarte, Bárbara; Vieira, MicaelTo assess the effects of a group class physical exercise program on health-related quality of life (HRQOL), physical fitness and activity, and safety in early breast cancer women after treatment, a double phase trial [16-week control phase (CP) followed by a 16-week intervention phase (IP)] was designed. Outcomes were evaluated at baseline (T1), 8 (T2) and 16 (T3) weeks (CP), and 24 (T4) and 32 (T5) weeks (IP)....
Analysis of potential risk factors for multidrug-resistance at a burn unit
Cabral, Luís; Rodrigues, Leonor; Tavares, Ana Helena; Tomé, Gonçalo; Caetano, Marisa; Chaves, Catarina; Afreixo, VeraBackground: Infections by multidrug-resistant (MDR) microorganisms are associated with increased morbidity and mortality in burn patients. This study aimed to analyze the evolution of MDR bacteria over a five-year period at Coimbra Burns Unit (CBU) in Portugal, seeking to assess the possible associations of specific bacteria with presumed risk factors. Methods: The data obtained consisted of identified bacteria...