40 documents found, page 1 of 4
Nefropatia Diabética
Bouça, B; Bogalho, AP; Agapito, AA Nefropatia Diabética (ND) é a principal causa de doença renal crónica estádio 5. O aumento da albuminúria é considerado o pilar da fisiopatologia da ND, mas não é um biomarcador específico ou preditor da história natural da doença. A otimização do controlo glicémico é fundamental na prevenção do aparecimento e da progressão da nefropatia. No entanto, muitos outros fatores demonstraram interferir na evolução d...
Quality of Life Among Adults with Repaired Tetralogy of Fallot: a Literature Re...
Rodrigues, C; Silva, M; Cerejo, R; Rodrigues, R; Sousa, L; Trigo, C; Branco, LM; Agapito, A; Fragata, JTetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. Survival into adulthood is currently expected following surgical repair, leading to a growing population of adults with repaired TOF. In this literature review, we aim to summarize the current state of knowledge on the quality of life of adults with repaired TOF. A search was conducted on PubMed and results were reviewed for articles...
POEMS Syndrome: a Rare Cause of Adrenal Insufficiency in a Young Male
Prokop, J; Estorninho, J; Marote, S; Sabino, T; Botelho de Sousa, A; Silva, E; Agapito, ASummary: POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes) is a rare multisystemic disease. Clinical presentation is variable, the only mandatory criteria being polyneuropathy and monoclonal gammapathy in association with one major and one minor criterion. Primary adrenal insufficiency is rarely reported. We describe a case of a 33-year-old patient, in whom the p...
Bicuspid Aortic Valve Aortopathies: an Hemodynamics Characterization in Dilated...
Oliveira, D; Aguiar Rosa, S; Tiago, J; Cruz Ferreira, R; Agapito, A; Sequeira, ABicuspid aortic valve (BAV) aortopathy remains of difficult clinical management due to its heterogeneity and further assessment of related aortic hemodynamics is necessary. The aim of this study was to assess systolic hemodynamic indexes and wall stresses in patients with diverse BAV phenotypes and dilated ascending aortas. The aortic geometry was reconstructed from patient-specific images while the aortic valv...
Prognostic Power of Anaerobic Threshold Parameters in Patients with Transpositi...
Valentim Gonçalves, A; Mano, T; Agapito, A; Aguiar Rosa, S; Sousa, L; Rio, P; Oliveira, JA; Monteiro, A; Pereira-da-Silva, T; Ilhão Moreira, RINTRODUCTION: Both transposition of the great arteries (TGA) previously submitted to a Senning/Mustard procedure and congenitally corrected TGA (cc-TGA) have the systemic circulation supported by the morphological right ventricle, thereby rendering these patients to heart failure events risk. The aim of this study was to evaluate cardiopulmonary exercise test parameters for stratifying the risk of heart failure...
Gitelman Syndrome and Primary Hyperparathyroidism: a Rare Association
Rego, T; Fonseca, F; Cerqueira, R; Agapito, AGitelman syndrome(GS) is a rare autosomal recessive salt-losing tubulopathy of young adults, characterised by hypokalaemia, hypomagnesaemia, hypocalciuria and secondary hyperaldosteronism. Hypercalcaemia due to hypocalciuria in these patients is extremely rare.A 25-year-old healthy woman was referred to the Endocrinology clinic for evaluation of persistent hypokalaemia. She presented with fatigue, myalgias, cra...
RoPE Score As a Predictor of Recurrent Ischemic Events After Percutaneous Paten...
Morais, LA; Sousa, L; Fiarresga, A; Martins, JD; Timóteo, AT; Viveiros Monteiro, A; Soares, C; Agapito, A; Pinto, MF; Cruz Ferreira, RThe benefits of patent foramen ovale (PFO) closure for cryptogenic stroke secondary prevention are still debated. The Risk of Paradoxical Embolism (RoPE) study developed a score to improve patient selection for this procedure. We proposed to assess the validity of this score to assess the prognostic impact of PFO closure.From 2000 to 2014, all consecutive patients submitted to PFO closure were included in a pro...
Uhl's Disease: an Uncommon Presentation of a Rare Disease
Aguiar Rosa, S; Agapito, A; António, M; de Sousa, L; Oliveira, JA; Laranjo, S; Martins, S; Jalles Tavares, N; Pinto, MF; Cruz Ferreira, RUhl's disease, also known as Uhl anomaly, is a rare disease secondary to selective but uncontrolled apoptosis of right ventricular myocytes during the perinatal period, after complete cardiac development, leading to the absence of right ventricular myocardium and the direct apposition of endocardium to epicardium without a myocardial layer in between, resulting in right ventricular failure. The present paper de...
Congenital Heart Disease in Adults: Assessment of Functional Capacity Using Car...
Aguiar Rosa, S; Agapito, A; Soares, RM; Sousa, L; Oliveira, JA; Abreu, A; Silva, AS; Alves, S; Aidos, H; Pinto, MF; Cruz Ferreira, RAIM: The aim of the study was to compare functional capacity in different types of congenital heart disease (CHD), as assessed by cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis was performed of adult patients with CHD who had undergone CPET in a single tertiary center. Diagnoses were divided into repaired tetralogy of Fallot, transposition of the great arteries (TGA) after Senning or...
ARMC5 Mutation in a Portuguese Family with Primary Bilateral Macronodular Adren...
Rego, T; Fonseca, F; Espiard, S; Perlemoine, K; Bertherat, J; Agapito, ASUMMARY: PBMAH is a rare etiology of Cushing syndrome (CS). Familial clustering suggested a genetic cause that was recently confirmed, after identification of inactivating germline mutations in armadillo repeat-containing 5 (ARMC5) gene. A 70-year-old female patient was admitted due to left femoral neck fracture in May 2014, in Orthopedics Department. During hospitalization, hypertension (HTA) and hypokalemia w...