5 documents found, page 1 of 1
The interface of science: the case for a broader definition of research management
Agostinho, Marta; Alves, Catarina Moniz; Aresta, Sandra; Borrego, Filipa; Borlido-Santos, Júlio; Cortez, João; Costa, Tatiana Lima; Lopes, José AntónioThis paper results from on-going reflection within the practitioners group Plataforma de Interface à Ciência (Platform of Professionals at the Interface of Science), an informal nationwide network in Portugal that brings together professionals involved in a large scope of activities related to research management, knowledge transfer and science communication. Due to the wide scope of functions and profiles of t...
Ciência e arte, SciArt: museus, laboratórios, cientistas e artistas
Agostinho, Marta; Casaleiro, Pedro[...] the scientist sets out to explain why, according to logical analysis, and expresses the outcomes through systematic exposition, while the artist, on a wholly divergent course, plays imaginative visual music on the melodies and harmonies of structural intuitions without being accountable for the kind of logical scrutiny that decrees rightness and wrongness [...]. (Kemp 2000, 2)Science and art both rely on ...
A DNA fragment of Desulfovibrio gigas genome containing replication origin rela...
Broco, Manuela; Oliveira, Solange; Silva, Gabriela; Agostinho, Marta; Rodrigues-Pousada, ClaudinaThe nucleotide sequence of a 10,772 base pair (bp) region from Desulfovibrio gigas genome was determined. This sequence, which is adjacent to the region containing the coding units for the metalloproteins rubredoxin-oxygen oxidoreductase (ROO) and rubredoxin, includes the flavodoxin gene. Additionally, it also contains four open reading frames (ORFs) related to genes frequently found in replication origin regio...
Molecular cloning of the gene encoding flavoredoxin, a flavoprotein from Desulf...
Agostinho, Marta; Oliveira, Solange; Broco, Manuela; Liu, M.Y.; LeGall, Jean; Rodrigues-Pousada, ClaudinaSulfate-reducing bacteria are rich in unique redox proteins and electron carriers that participate in a variety of essential pathways. Several studies have been carried out to characterize these proteins, but the structure and function of many are poorly understood. Many Desulfovibrio species can grow using hydrogen as the sole energy source, indicating that the oxidation of hydrogen with sulfite as the termina...
Conjugation of human topoisomerase 2A with small ubiquitin-like modifiers 2/3 i...
Agostinho, Marta; Santos, Vera; Ferreira, Fernando; Cardoso, Joana; Costa, Rafael; Pinheiro, Inês; Rino, José; Jaffray, Ellis; Hay, RonaldType 2 topoisomerases, in particular the A isoform in human cells, play a key role in cohesion and sister chromatid separation during mitosis. These enzymes are thus vital for cycling cells and are obvious targets in cancer chemotherapy. Evidence obtained in yeast and Xenopus model systems indicates that conjugation of topoisomerase 2 with small ubiquitin-like modifier (SUMO) proteins is required for its mitoti...