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One year of COVID‐19: a longitudinal study of individual and relational factors...

Relvas, Ana Paula; Portugal, Alda; Lacomba‐Trejo, Laura; Major, Sofia; Sotero, Luciana; Agostinho, Rafaela; Moreira, Marta; Randall, Ashley K.

<jats:title>Abstract</jats:title><jats:p>This longitudinal study explored the impact of COVID‐19 on individuals in romantic relationships. The sample spans three waves: first confinement (<jats:italic>n</jats:italic> = 52), deconfinement (<jats:italic>n</jats:italic> = 49), and second confinement (<jats:italic>n</jats:italic> = 26). The study tested sociodemographic factors, psychological adjustment (anxiety, d...


Regulation of Ras signaling by S-Nitrosylation

S, Simão; Agostinho, Rafaela; Martínez-Ruiz, Antonio; Araújo, Inês Maria

Ras are a family of small GTPases that function as signal transduction mediators and are involved in cell proliferation, migration, differentiation and survival. The significance of Ras is further evidenced by the fact that Ras genes are among the most mutated oncogenes in different types of cancers. After translation, Ras proteins can be targets of post-translational modifications (PTM), which can alter the in...


New fluorescent probes based on gallium(III) corrole complexes for the recognit...

Santos, Carla I.M.; Santiago, Ana M.; Araújo, Ana R.L.; Pinto, Sandra; Agostinho, Rafaela; Simão, Sónia; Azevedo, Tomás Pais de; Antunes, Catarina

In this work, three fluorescent probes for detection of hydrogen sulfide (H2S) where prepared based on gallium (III) corrole complexes bearing nitro groups at beta-pyrrolic positions. Two of the compounds selected, the 3-nitro5,10,15- tris(pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-NO2) and the 3,17-dinitro-5,10,15-tris (pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-2NO2) present one and tw...


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