4 documents found, page 1 of 1
The antiproliferative peptide Ctn[15-34] is active against multidrug-resistant ...
Aguiar, Francisca Lidiane Linhares de; Cavalcante, Carolina Sidrim De Paula; Fontenelle, Raquel Oliveira dos Santos; Falcão, Cláudio Borgesims: Crotalicidin (Ctn), a cathelicidin-related antimicrobial peptide from theSouth American rattlesnake venom gland, and its C-terminal Ctn[15-34] fragment,have exhibited important activities against micro-organisms, trypanosomatidprotozoa and certain lines of tumour cells. Herein, the activity against clinicalstrains of fluconazole-resistant Candida albicans and of amphotericin B andfluconazole-resistant Crypto...
Atividade antifúngica das crotalicidinas contra leveduras resistentes e caracte...
Aguiar, Francisca Lidiane Linhares deCrotalicidin (Ctn), a cathelicidin-related antimicrobial peptide from the venom gland of a South American rattlesnake, as well as its C-terminal Ctn[15-34] fragment, have shown important activities against micro-organisms, trypanosomatid protozoa and certain lines of tumor cells. Herein, the activity against clinical strains of fluconazoleresistant Candida albicans and of amphotericin B and fluconazole-resistan...
Antibiofilm activity on Candida albicans and mechanism of action on biomembrane...
Aguiar, Francisca Lidiane Linhares de; Santos, Nuno C.; de Paula Cavalcante, Carolina Sidrim; Andreu, David; Baptista, Gandhi Radis; Gonçalves, SóniaCtn[15-34], the C-terminal fragment of crotalicidin, an antimicrobial peptide from the South American rattlesnake Crotalus durissus terrificus venom, displays remarkable anti-infective and anti-proliferative activities. Herein, its activity on Candida albicans biofilms and its interaction with the cytoplasmic membrane of the fungal cell and with a biomembrane model in vitro was investigated. A standard C. albic...
Effect of essential oils from Mangifera indica L. cultivars on the antifungal s...
Fontenelle, Raquel Oliveira dos Santos; Sobrinho, Antonio Carlos Nogueira; Soares, Bruna Vieira; Aguiar, Francisca Lidiane Linhares deThis work reports the chemical study, and anti- Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti- Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth micro...