10 documents found, page 1 of 1

Development of a microfluidic paper-based device for aluminium quantification i...

In this work, the development of a simple and low-cost microfluidic paper-based analytical device (mPAD) for the colorimetric detection and quantification of aluminium in urine samples is presented. Aluminium exposure is an increasing public health concern due to its potential neurotoxic effects and its association with disorders such as Alzheimer’s disease and autism spectrum disorder. In this context, it may ...

A public health tool for monitoring aluminium levels in environmental and biolo...

Aluminium is an element with potential toxic effects, particularly when exposure exceeds safe limits. Drinking water is a key matrix for assessing environmental contamination and human exposure, since long-term intake of high aluminium concentrations has been associated with several health issues, including Alzheimer’s disease. Additionally, monitoring aluminium in urine provides an important measure of cumulat...

Development of a microfluidic paper-based device for aluminium quantification i...

Development of a microfluidic paper-based sensor for aluminium assessment in wa...

Aluminium is one of the most abundant metal ions in soil and its leaching into groundwater is an expected consequence. Monitoring the presence of Al3+ in water sources used for domestic consumption water is crucial, considering its relationship with some neurogenetic disorders, namely Alzheimer’s and Parkinson’s diseases, autism, and multiple sclerosis. In this work, the design and development of a novel microf...

Use of a rhodamine-based chelator in a microfluidic paper-based analytical devi...

This work describes the development of a microfluidic paper-based analytical device (μPAD) for the determination of copper in fresh and marine waters. A functionalized rhodamine-based chelator was synthesized and used as a chromogenic reagent, forming a highly intense pink complex with the analyte. The aim was to create a paper device that offers optimal performance and provides in-situ, rapid and cost-effectiv...

Iron determination in natural waters using a synthesised 3-hydroxy-4-pyridione ...

This work describes the development of an iron sensor based on a microfluidic paper-based technique, to attain iron quantification in natural waters. A new water-soluble naphthalene-3-hydroxy-4-pyridione ligand was used as a colour reagent, as it formed an orange complex with iron. As a newly described ligand, several chemical and physical parameters, namely, the sample and reagent volumes and reagent concentra...

Salivary calcium determination with a specially developed microfluidic paper-ba...

The calcium monitoring in the body not only anticipates several potential diseases (osteoporosis, kidney stones or high blood pressure) but also helps to improve target therapies and follow-up the patient's health status. Calcium monitoring is essential for the diagnosis of one of the most common endocrine disorders worldwide, namely hyperparathyroidism. So, in this work, a new Point-of-care test (POC-test) usi...

Development of a microfluidic paper-based analytical device for magnesium deter...

In this work, a microfluidic paper-based analytical device (μPAD) was developed for magnesium determination in saliva samples. The idea was to develop a fast and simple method for biological magnesium quantification targeting saliva as an easy to collect and non-invasive alternative to blood or urine samples. The μPAD approach was chosen due to its advantages, namely ideally suited to conduct on-location determ...

Quantification of salivary magnesium using a microfluidic paper based analytica...

Design and development of a mPAD device for magnesium determination in saliva