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Tuberculosis: integrated studies for a complex disease 2050

Rezaei, Nima; Hosseini, Nastaran-Sadat; Saghazadeh, Amene; Fateh, Abolfazl; Duse, Adriano; Ahmad, Aijaz; Braley, Alexander E.; Tahta, Alican

Tuberculosis (TB) has been a disease for centuries with various challenges [1]. Like other places where challenges and opportunities come together, TB challenges were the inspiration for the scientific community to mobilize different groups for the purpose of interest. For example, with the emergence of drug resistance, there has been a huge volume of research on the discovery of new medicines and drug delivery...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Synergistic Interactions of Eugenol-tosylate and Its Congeners with Fluconazole...

Ahmad, Aijaz; Wani, Mohmmad Younus; Khan, Amber; Manzoor, Nikhat; Molepo, Julitha

We previously reported the antifungal properties of a monoterpene phenol "Eugenol" against different Candida strains and have observed that the addition of methyl group to eugenol drastically increased its antimicrobial potency. Based on the results and the importance of medicinal synthetic chemistry, we synthesized eugenol-tosylate and its congeners (E1-E6) and tested their antifungal activity against differen...


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