2 documents found, page 1 of 1
Uncommon Oral Cleft in Wolf-Hirschhorn Syndrome
Aquino,Sibele Nascimento de; Machado,Renato A.; Paranaíba,Lívia Maris R.; Coletta,Ricardo D.; Aguiar,Marcos J. Burle de; Fernandes,CassandroWolf-Hirschhorn syndrome (WHS) is a syndrome with craniofacial and systemic abnormalities, which is related to 4p deletion. A 3-month old girl with an undiagnosed syndrome was referred for evaluation of the cleft lip and palate. Hypotonia, short stature, cardiac malformation, hypertrophied clitoris, and atypical thumb of both hands was observed. Microcephaly, low-set ear, prominent glabella, downslanting palpeb...
Frequency of Cancer in First-Degree Relatives of Patients with Cleft Lip and/or...
Lima,Leonardo Santos; Silverio,Matheus de Oliveira; Swerts,Mario Sergio Oliveira; Aquino,Sibele Nascimento de; Martelli,Daniella Reis BarbosaCongenital malformations and cancer may share common etiological factors and the association between nonsyndromic cleft lip and/or palate (NSCL/P) and cancers has been observed in different studies. The objective of this study was to evaluate the frequency of cancer in relatives of patients with NSCL/P. This investigation was a cross-sectional, case-controlled study, evaluating 358 patients with NSCL/P treated ...