3 documents found, page 1 of 1
Epidemiology of enteroaggregative Escherichia coli infections and associated ou...
Rogawski, Elizabeth T.; Guerrant, Richard L.; Havt, Alexandre; Lima, Ila F. N.; Medeiros, Pedro H. Q. S.; Seidman, Jessica C.; McCormick, Benjamin J. J.Background Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight...
Use of antibiotics in children younger than two years in eight countries : a pr...
Rogawski, Elizabeth T.; Platts-Mills, James A.; Seidman, Jessica C.; John, Sushil; Mahfuz, Mustafa; Ulak, Manjeswori; Shrestha, Sanjaya K.Objective To describe the frequency and factors associated with antibiotic use in early childhood, and estimate the proportion of diarrhoea and respiratory illnesses episodes treated with antibiotics. Methods Between 2009 and 2014, we followed 2134 children from eight sites in Bangladesh, Brazil, India, Nepal, Pakistan, Peru, South Africa and the United Republic of Tanzania, enrolled in the MAL-ED birth cohort ...
Causal pathways from enteropathogens to environmental enteropathy : findings fr...
Kosek, Margaret N.; Ahmed, Tahmeed; Bhutta, Zulfiquar; Caulfield, Laura; Guerrant, Richard; Houpt, Eric; Kang, Gagandeep; Lee, Gwenyth; Lima, AldoBackground: Environmentalenteropathy (EE),the adverseimpact offrequent and numerous entericinfections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth failure in children in low- and middle-income populations. A theory-driven systems model to critically evaluate pathways through which enteropathogens, gut permeability, and...