6 documents found, page 1 of 1
Evaluation of radiotherapy doses in pediatric patients with Hodgkin Lymphoma: M...
Mota, Inês; Cravo Sá, Ana; Costa, Fernando; Monteiro, Armanda; Aires, Fátima; Faria, IsabelBackground: Hodgkin lymphoma (HL) is one of the most common cancers in children, and radiotherapy (RT) is a crucial part of treatment [1,2]. However, the risk of late effects, such as cardiotoxicity and secondary malignant neoplasms, is a concern due to radiation exposure to critical organs [2-8]. Advanced dose calculation methods, such as Monte Carlo Methods (MCMs), can improve dosimetry accuracy and help mini...
Radiotherapy metastatic prostate cancer cell lines treated with gold nanorods m...
Soares, Sílvia; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Faria, Isabel; Sales, Goreti; Correa-Duarte, Miguel A.; Guerreiro, SusanaMicroRNA (miRNA) modulation has been identified as a promising strategy for improving the response of human prostate cancer (PCa) to radiotherapy (RT). Studies have shown that mimics or inhibitors of miRNAs could modulate the sensitivity of PCa cells to RT. In addition, pegylated gold nanoparticles have been studied as a therapeutic approach to treat PCa cells and/or vehicles for carrying miRNAs to the inside o...
Application of Gold Nanoparticles as Radiosensitizer for Metastatic Prostate Ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, M. Goreti F.; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Application of gold nanoparticles as radiosensitizer for metastatic prostate ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, Maria Goreti; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Application of gold nanoparticles as radiosensitizer for metastatic prostate ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, Maria Goreti; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Results of Surgery in Lung Cancer – A Retrospective Study of a Single Center Ex...
Costa, Rita; Aires, Fátima; Máximo, José; Pissarra, Diana; Maciel, João; Marques, Margarida; Fernandes, Pedro; Pinho, PauloObjectives: Surgery provides the best chance for cure in patients with non-small-cell lung cancer stage I or II, but only a small portion of all new cases diagnosed are eventually suitable for surgical resection. Our goal was to appraise the surgical outcomes including survival and progression rates in patientswith histological diagnosis of lung cancer. Methods: Between 1st August 2012 and 30th June 2018, the p...