24 documents found, page 1 of 3
Interplay between western diet and mammary cancer: data from a chemically-induc...
Silva, J; Azevedo, T; Aires, I; Peixoto, F; Neuparth, MJ; Faustino-Rocha, AI; Duarte, JA; Oliveira, PABackground/Aim: This study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N- nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), a...
ffect of resistance exercise training on blood antioxidant capacity in rats und...
Anjos, J; Santos, S; Anjos, L; Aires, I; Garcias, I; Azevedo, C; Silva, M; Oliveira, PA; Faustino-Rocha, Ana I; Peixoto, FIntroduction: Doxorubicin (DOX) is an efficient chemotherapeutic drug used in the treatment of several types of cancer, such as breast cancer. DOX causes cardiotoxicity that leads to cardiac inflammation and remodeling as a result of oxidative stress and impaired mitochondrial function. Several studies observed a beneficial effect of exercise training on antioxidants, due to upregulation of the activity of some...
Resistance exercise in an animal model of mammary cancer treated with doxorubic...
Anjos, L; Santos, S; Anjos, J; Aires, I; Garcias, I; Azevedo, C; Moreira-Gonçlaves, M; Ferreira, R; Duarte, JA; Oliveira, PA; Faustino-Rocha, Ana IIntroduction: Doxorubicin (DOX) is one of the most effective antitumor drugs for breast cancer treatment. DOX is associated to high toxicity in multiple organs and tissues. This study aimed to assess the effects of resistance exercise training (RET) in the hematological parameters of rats with mammary cancer treated with DOX. Material & Methods: Wistar Rats were divided into six groups: I (sedentary, SED), II (...
Effect of resistance exercise training on blood antioxidant capacity in rats un...
Anjos, J; Santos, SD; Anjos, L; Aires, I; Garcias, I; Azevedo, C; Silva, M; Oliveira, PA; Faustino-Rocha, AI; Peixoto, FIntroduction: Doxorubicin (DOX) is an efficient chemotherapeutic drug used in the treatment of several types of cancer, such as breast cancer. DOX causes cardiotoxicity that leads to cardiac inflammation and remodeling as a result of oxidative stress and impaired mitochondrial function. Several studies observed a beneficial effect of exercise training on antioxidants, due to upregulation of the activity of some...
Resistance exercise in an animal model of mammary cancer treated with doxorubic...
Anjos, L; Santos, SD; Anjos, J; Aires, I; Garcias, I; Azevedo, C; Gonçalves-Moreira, D; Ferreira, R; Duarte, JA; Oliveira, PA; Faustino-Rocha, AIIntroduction: Doxorubicin (DOX) is one of the most effective antitumor drugs for breast cancer treatment. DOX is associated to high toxicity in multiple organs and tissues. This study aimed to assess the effects of resistance exercise training (RET) in the hematological parameters of rats with mammary cancer treated with DOX. Material & Methods: Wistar Rats were divided into six groups: I (sedentary, SED), II (...
Adenovirus Infection in a Kidney–Pancreatic Transplant Recipient: Case Report
Damas, J; Vida, AC; Marques, J; Caeiro, F; Aires, I; Dias, JM; Bigotte Vieira, M; Cotovio, P; Magriço, R; Ferreira, AAdenovirus infection in transplant recipients may present from asymptomatic viremia to multisystemic involvement. Most frequently, it occurs in the first year after a kidney transplant, and it is secondary to the reactivation of latent disease. However, primary infection may occur, and disseminated disease is more common when related to primary infection. Kidney involvement may be confirmed by biopsy, although ...
Predicting Function Delay with a Machine Learning Model: Improve the Long-term ...
Vigia, E; Ramalhete, L; Barros, I; Chumbinho, B; Filipe, E; Pena, A; Bicho, L; Nobre, A; Carrelha, S; Corado, S; Sobral, M; Lamelas, J; Santos Coelho, JThe impact of delayed graft function on outcomes following various solid organ transplants is well documented and addressed in the literature. Delayed graft function following various solid organ transplants is associated with both short- and long-term graft survival issues. In a retrospective cohort study including 106 patients we evaluated whether pancreas graft survival differs according to moment of insulin...
Improvement of Mineral and Bone Disorders After Renal Transplantation
Ferreira, AC; Mendes, M; Silva, C; Cotovio, P; Aires, I; Navarro, D; Caeiro, F; Ramos, R; Salvador, R; Correia, B; Cabral, G; Nolasco, F; Ferreira, ABackground: Posttransplant mineral and bone diseases are causes of fractures, and their association with cardiovascular events is being studied. Methods: We analyzed the evolution of biochemical, histological, and imaging parameters pre- and 1 y post-renal transplantation in 69 patients and correlated mineral and bone findings with coronary calcifications. At inclusion and after 12 mo, clinical data and echocar...
Combined Lung-Kidney Transplantation: First Case in Portugal
Silva, D; Dantas, C; Santos, AS; Silva, C; Aires, I; Remédio, F; Carrelhas, S; Pena, A; Eurico Reis, J; Calvinho, P; Semedo, L; Cardoso, J; Nolasco, FA significant dysfunction of another organ is usually considered an absolute contraindication for lung transplantation, unless multiorgan transplantation is indicated and practical, as is the case of combined lung-kidney transplantation. Few cases of combined lung-kidney transplantation have been described in the literature; however, it is known that, in certain cases, it is the only way to offer an opportunity...
Bone Densitometry Versus Bone Histomorphometry in Renal Transplanted Patients: ...
Ferreira, AC; Mendes, M; Silva, C; Cotovio, P; Aires, I; Navarro, D; Caeiro, F; Salvador, R; Correia, B; Cabral, G; Nolasco, F; Ferreira, ABone loss leads to increase risk of fractures in renal transplantation. The aim of this study was to analyse the relationship between bone densitometry (DXA) findings, bone histomorphometry and bone-related molecules 1-year after renal transplantation. We performed a cross-sectional study of de novo renal transplanted patients that agreed to perform a bone biopsy and a DXA examination 1 year after transplantati...