9 documents found, page 1 of 1
Risk Factors of Acute T -Cell Mediated and Borderline Rejection Diagnosed in Ea...
Roldão,Marisa; Vida,Ana Carlota; Dias,Joana Monteiro; Vieira,Miguel Bigotte; Magriço,Rita; Silva,Cecília; Caeiro,Fernando; Aires,Inês; Ferreira,AníbalAbstract Introduction: Acute graft rejection remains one of the main causes of graft dysfunction and premature loss. Understanding the factors affecting graft rejection is essential to promote graft survival. Our study aimed to determine the incidence and assess risk factors of acute T‑cell mediated rejection (TCMR) and borderline rejection in early protocol kidney transplant biopsies. Methods: Retrospective si...
NAU ‑ New Areas of Unifying Interest for CKD: A Multidisciplinary Expert Opinio...
Malheiro,Jorge; Araújo,Francisco; Nunes,Andreia; Almeida⁵,Clara; Aires,Inês; Nobre,João Pedro; Neves,João Sérgio; Dias,Jordana; Vieira,Miguel BigotteAbstract Introduction: The global prevalence of chronic kidney disease (CKD) is rising exponentially. While patient awareness of CKD remains low, we studied the physicians’ awareness and how globally it can be improved. We aimed to evaluate the awareness and consensus of physicians on the screening, diagnosis and clinical management of CKD, thus identifying which areas should be the subject of educational or re...
Neutropenic enterocolitis (typhlitis) in a kidney transplant patient: A case re...
Alves,Rita Valério; Falcão,Luís; Soares,Elsa; Mendes,Milena; Cotovio,Patrícia; Caeiro,Fernando; Aires,Inês; Silva,Cecília; Remédio,FranciscoTyphlitis is a clinical entity rare in adults, reported in immunosuppressed patients. It is a life-threatening condition that occurs in neutropenic patients due to compromised integrity of the bowel wall and its exact pathogenesis is not completely understood. We report a 35-year-old man with a post deceased donor renal and pancreas transplantation status who presented fever and febrile neutropenia. Three days ...
Antibody mediated rejection. Evidence based medicine. What is the current evide...
Menezes,Maria do Mar; Aires,Inês; Nolasco,FernandoAntibody mediated rejection (ABMR) is a major cause of kidney graft loss. The ideal treatment remains unknown, is not standardized and there is little evidence to support the use of any specific therapy. This paper aims to reflect on the current state of this challenging diagnosis, either active or chronic active ABMR, and its treatment options. The current treatments encompass plasma exchange, steroids, intrav...
Simultaneous pancreas-kidney transplantation after liver transplantation: first...
Soares,Elsa; Alves,Rita Valério; Cotovio,Patrícia; Caeiro,Fernando; Aires,Inês; Bigotte,Miguel; Silva,Cecília; Pena,Ana; Bicho,Luís; Martins,AméricoSimultaneous kidney pancreas transplantation, if feasible, is the treatment of choice for the management of end-stage renal disease in patients with type 1 diabetes. This intervention can offer glycemic control and might also stabilize or even reverse some of the metabolic complications of diabetes. Chronic kidney disease has become a critical problem in orthotopic liver transplantation due to multiple risk fac...
Are high flow arteriovenous accesses associated with worse haemodialysis?
Laranjinha,Ivo; Matias,Patrícia; Azevedo,Ana; Navarro,David; Ferreira,Carina; Amaral,Tiago; Mendes,Marco; Aires,Inês; Jorge,Cristina; Gil,CéliaABSTRACT Introduction: An arteriovenous (AV) access flow (Qa) of 400 mL/min is usually sufficient for an effective hemodialysis (HD), but some accesses continue developing and become high flow accesses (HFA). Some authors postulated that an HFA might shift a significant portion of dialyzed blood from the cardiac output, which could decrease HD efficiency and lead to volume overload. Objective: The aim of our st...
A rare malignancy in the post-transplant period: Myeloma cast nephropathy
Mesquita,Isabel; Viana,Helena; Possante,Marília; João,Cristina; Carvalho,Susana; Silva,Cecília; Aires,Inês; Ferreira,Aníbal; Remédio,FranciscoMyeloma-associated renal disorders are rare events among renal transplants and can occur as recurrent or de novo disease. We describe an unusual case of renal allograft dysfunction due to myeloma cast nephropathy occurring 19 years after having received a renal transplant in a patient with no prior history of multiple myeloma or monoclonal gammopathy preceding transplantation. Our patient was treated with five ...
Benefits of selective vitamin D receptor activators in kidney transplanted pati...
Ferreira,Aníbal; Aires,Inês; Nolasco,Fernando; Machado,Domingos; Macário,Fernando; Neves,Pedro L.; Costa,António G.; Cabrita,António M. N.; Castro,RuiSevere chronic kidney disease may lead to disturbances, such as hyperphosphatemia, increased secretion of fibroblast growth factor-23 (FGF-23) and vitamin D deficiency. These may increase plasmatic levels of parathyroid hormone, and decrease plasmatic levels of calcium. Altogether, these may contribute to the development of secondary hyperparathyroidism, and to abnormalities in mineral metabolism. Kidney transp...
Long nocturnal dialysis: A single-centre experience
Navarro,David; Ferreira,Ana Carina; Gonçalves,Carina; Jorge,Cristina; Gil,Célia; Aires,Inês; Matias,Patrícia; Mendes,Marco; Azevedo,Ana; Gomes,FernandaThe institution of intensified dialysis regimens (as long treatment time, with reduced ultrafiltration per hour) has been associated with decreased morbidity and mortality in patients with end-stage chronic kidney disease. The performance of the haemodialysis session during the night interval emerged as logical, since it is an idle period, and has been associated with better small molecule dialysis, better bl...