2 documents found, page 1 of 1
Gut as an alternative entry route for SARS-CoV-2: current evidence and uncertai...
Clerbaux, Laure Alix; Mayasich, Sally A.; Munoz Pineiro, Amalia; Soares, Helena; Petrillo, Mauro; Albertini, Maria Cristina; Lanthier, NicolasThe gut has been proposed as a potential alternative entry route for SARS-CoV-2. This was mainly based on the high levels of SARS-CoV-2 receptor expressed in the gastrointestinal (GI) tract, the observations of GI disorders (such as diarrhea) in some COVID-19 patients and the detection of SARS-CoV-2 RNA in feces. However, the underlying mechanisms remain poorly understood. It has been proposed that SARS-CoV-2 c...
Clinical, histological and molecular profiling of different stages of alcohol-r...
Ventura-Cots, Meritxell; Argemi, Josepmaria; Jones, Patricia D; Lackner, Carolin; El Hag, Mohamed; Abraldes, Juan G; Alvarado, Edilmar; Clemente, AnaObjective: Alcohol-related liver disease (ALD) ranges from never-decompensated ALD (ndALD) to the life-threatening decompensated phenotype, known as alcohol-related hepatitis (AH). A multidimensional study of the clinical, histological and molecular features of these subtypes is lacking. Design: Two large cohorts of patients were recruited in an international, observational multicentre study: a retrospective co...