4 documents found, page 1 of 1

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Cyperus spp.: A Review on Phytochemical Composition, Biological Activity, and H...

Taheri, Y; Herrera-Bravo, J; Huala, L; Salazar, LA; Sharifi-Rad, J; Akram, M; Shahzad, K; Melgar-Lalanne, G; Baghalpour, N; Tamimi, K

Cyperaceae are a plant family of grass-like monocots, comprising 5600 species with a cosmopolitan distribution in temperate and tropical regions. Phytochemically, Cyperus is one of the most promising health supplementing genera of the Cyperaceae family, housing ˜950 species, with Cyperus rotundus L. being the most reported species in pharmacological studies. The traditional uses of Cyperus spp. have been report...


Chitosan nanoparticles as a promising tool in nanomedicine with particular emph...

Sharifi-Rad, J; Quispe, C; Butnariu, M; Rotariu, LS; Sytar, O; Sestito, S; Rapposelli, S; Akram, M; Iqbal, M; Krishna, A; Kumar, NVA; Braga, SS

The study describes the current state of knowledge on nanotechnology and its utilization in medicine. The focus in this manuscript was on the properties, usage safety, and potentially valuable applications of chitosan-based nanomaterials. Chitosan nanoparticles have high importance in nanomedicine, biomedical engineering, discovery and development of new drugs. The manuscript reviewed the new studies regarding ...


Therapeutic Potential of Isoflavones with an Emphasis on Daidzein

Alshehri, MM; Sharifi-Rad, J; Herrera-Bravo, J; Jara, EL; Salazar, LA; Kregiel, D; Uprety, Y; Akram, M; Iqbal, M; Martorell, M; Torrens-Mas, M; Pons, DG

Daidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and estrogen receptor (ER) complex. Hence, daidzein puts forth shielding effects against a great number of diseases, especially those associated with the control of estr...


Insights on the use of a-lipoic acid for therapeutic purposes

Salehi, B; Yilmaz, YB; Antika, G; Boyunegmez, TT; Fawzi, MM; Lobine, D; Akram, M; Riaz, M; Capanoglu, E; Sharopov, F; Martins, N; Cho, WC

a-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. It has various properties, among them great antioxidant potential and is widely used as a racemic drug for diabetic polyneuropathy-associated pain and paresthesia. Naturally, ALA is located in mitochondria, where it is used as a cofactor for pyruvate dehydrogenase (PDH) and a-ketoglutarate dehydrogenase co...


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