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An international multidisciplinary consensus statement on MAFLD and the risk of...

Zhou, Xiao-Dong; Targher, Giovanni; Byrne, Christopher D.; Somers, Virend; Kim, Seung Up; Chahal, C. Anwar A.; Wong, Vincent Wai-Sun; Cai, Jingjing

Background: Fatty liver disease in the absence of excessive alcohol consumption is an increasingly common condition with a global prevalence of ~ 25-30% and is also associated with cardiovascular disease (CVD). Since systemic metabolic dysfunction underlies its pathogenesis, the term metabolic (dysfunction)-associated fatty liver disease (MAFLD) has been proposed for this condition. MAFLD is closely intertwined...


The EASL–Lancet Liver Commission: protecting the next generation of Europeans a...

Karlsen, Tom H.; Sheron, Nick; Zelber-Sagi, Shira; Carrieri, Patrizia; Dusheiko, Geoffrey; Bugianesi, Elisabetta; Pryke, Rachel; Hutchinson, Sharon J.

Liver diseases have become a major health threat across Europe, and the face of European hepatology is changing due to the cure of viral hepatitis C and the control of chronic viral hepatitis B, the increasingly widespread unhealthy use of alcohol, the epidemic of obesity, and undiagnosed or untreated liver disease in migrant populations. Consequently, Europe is facing a looming syndemic, in which socioeconomic...


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