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WHO global research priorities for antimicrobial resistance in human health

WHO Research Agenda for AMR in Human Health Collaborators; Bertagnolio, Silvia; Dobreva, Zlatina; Centner, Chad M.; Olaru, Ioana Diana; Donà, Daniele

The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treat...


A multicentre external quality assessment: A first step to standardise PCR prot...

Wilmes, Dunja; Hagen, Ferry; Verissimo, Cristina; Alanio, Alexandre; Rickerts, Volker; Buitrago, Maria José

Background: In-house real-time PCR (qPCR) is increasingly used to diagnose the so called endemic mycoses as commercial assays are not widely available. Objectives: To compare the performance of different molecular diagnostic assays for detecting Histoplasma capsulatum and Coccidioides spp. in five European reference laboratories. Methods: Two blinded external quality assessment (EQA) panels were sent to each la...


Large expert-curated database for benchmarking document similarity detection in...

Brown, Peter; Tan, Aik-Choon; El-Esawi, Mohamed A.; Liehr, Thomas; Blanck, Oliver; Gladue, Douglas P.; Almeida, Gabriel M. F.; Cernava, Tomislav

Made available in DSpace on 2020-12-11T01:57:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-29; Griffith University Gowonda HPC Cluster; Queensland Cyber Infrastructure Foundation; Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents tha...

Data: 2020   |   Origem: Oasisbr

ECMM CandiReg - A ready to use platform for outbreaks and epidemiological studies

Koehler, Philipp; Arendrup, Maiken Cavling; Arikan‐Akdagli, Sevtap; Bassetti, Matteo; Bretagne, Stéphane; Klingspor, Lena; Lagrou, Katrien

Background: Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Objectives: Triggered by the emergence of C auris and by increasing antifungal resistance rates...


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