As síndromes extrapiramidais, como a distonia, a acatisia e o parkinsonismo, são doenças do movimento descritas como efeito adverso dos antipsicóticos em idade adulta. A sua utilização tem-se disseminado entre as crianças e, como tal, também este tipo de sintomas, principalmente associados aos fármacos de primeira geração. A paliperidona é um antipsicótico de segunda geração aprovado para o tratamento da esquiz...
Urticaria multiforme (UM) is an allergic hypersensitivity reaction characterized by the acute onset of polycyclic and annular wheals with ecchymotic centers. It is more common in children under 4 years of age, who typically present with a pruritic rash and nontoxic appearance. The diagnosis is clinical. The condition usually has a favorable response to antihistamines and self-limited course. UM is probably unde...
Introduction: Screen use among adolescents has increased, with excessive screen time associated with poor sleep. Isolation due to the COVID-19 pandemic may have exacerbated these problems. This study aimed to characterize adolescents’ sleep and screen use behaviors during the COVID-19 pandemic lockdown. Methods: This was a multicenter, cross-sectional, descriptive study of adolescents aged 10 to 18 years evalua...
Pelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy of the central nervous system characterized by a developmental arrest in myelin formation. It is classified into five phenotypes, with different severity. The most common clinical features are nystagmus, spasticity, tremor, ataxia, and hypotonia. A 11-month-old child was referred to the Neuropediatric Unit due to nystagmus, hypotonia, and developm...
Urticaria multiforme (UM) is an allergic hypersensitivity reaction characterized by the acute onset of polycyclic and annular wheals with ecchymotic centers. It is more common in children under 4 years of age, who typically present with a pruritic rash and nontoxic appearance. The diagnosis is clinical. The condition usually has a favorable response to antihistamines and self-limited course. UM is probably unde...
Extrapyramidal symptoms (EPS), such as dystonia, akathisia, and parkinsonism, are movement disorders that have been described as a side effect of antipsychotic medications in adults. In children, their use has expanded, as have this type of symptoms, especially those caused by first-generation antipsychotics. Paliperidone is a second-generation drug approved for schizophrenia in adolescents. The authors describ...
Introduction: Screen use among adolescents has increased, with excessive screen time associated with poor sleep. Isolation due to the COVID-19 pandemic may have exacerbated these problems. This study aimed to characterize adolescents’ sleep and screen use behaviors during the COVID-19 pandemic lockdown.Methods: This was a multicenter, cross-sectional, descriptive study of adolescents aged 10 to 18 years evaluat...
Background: Viral respiratory infections may precipitate type 1 diabetes (T1D). A possible association between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, and the incidence of T1D is being determined. This study was carried out using Portuguese registries, aiming at examining temporal trends between COVID-19 and T1D.MethodsHospital data, comparing the in...
Background: Viral respiratory infections may precipitate type 1 diabetes (T1D). A possible association between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, and the incidence of T1D is being determined. This study was carried out using Portuguese registries, aiming at examining temporal trends between COVID-19 and T1D. Methods: Hospital data, comparing the...
COVID-19 usually has a mild course in the pediatric population. Several cutaneous manifestations of the condition have been reported, being chilblain-like lesions one of the most common in younger ages. These may manifest as erythematous or violaceous macules, mostly involving the toes and feet, but less frequently also the fingers and hands. These patients usually have a favorable outcome, with complete sponta...