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O papel do Instituto Nacional de Saúde Dr. Ricardo Jorge na avaliação e prevenç...

José, Silvia; Valério, Elisabete; Menezes, Carina; Dias, Elsa; Ferreira, Filipa; Albergaria, Isabel; Grossinho, José; Jordão, Luisa; Silva, Manuela

O papel do Instituto Nacional de Saúde Doutor Ricardo Jorge na avaliação e prevenção de riscos para a saúde pública (Vigilância e controlo da qualidade da água e areias).


Monitorização de Trihalometanos (THMs) em águas de consumo humano e piscina

José, Sílvia S.; Albergaria, Isabel; Silva, Zelinda; Cardoso, Ana Sofia; Rebelo, Helena

[PT] A água é essencial à vida, pelo que é fundamental e obrigatório garantir a sua qualidade química e microbiológica. O cloro é o desinfetante mais utilizado para prevenir o desenvolvimento na água de microrganismos, embora possam também ser utilizados outros desinfecantes, como por exemplo o bromo. Ambos os compostos podem reagir com a matéria orgânica presente na água originando subprodutos dos quais os mai...


Variants in the inflammatory IL6 and MPO genes modulate stroke susceptibility t...

Manso, Helena; Krug, Tiago; Sobral, João; Albergaria, Isabel; Gaspar, Gisela; Ferro, José M.; Oliveira, Sofia A.; Vicente, A.M.

There is substantial evidence that inflammation within the central nervous system contributes to stroke risk and recovery. Inflammatory conditions increase stroke risk, and the inflammatory response is of major importance in recovery and healing processes after stroke. We investigated the role of inflammatory genes IL1B, IL6, MPO, and TNF in stroke susceptibility and recovery in a population sample of 672 patie...


Influence of the APOE genotypes in some atherosclerotic risk factors.

Carmo Martins, Maria; Lima Faleiro, Luís; Rodrigues, Maria Odete; Albergaria, Isabel; Fonseca, Aidil

The aim of this work was to study the distribution of apolipoprotein E (APOE) genotypes and their association with some atherosclerotic risk factors, all of them modifiable: total, HDL and LDL cholesterol, triglycerides, systolic and diastolic blood pressure, BMI, waist circumference and smoking. The sample population was constituted of 672 healthy subjects recruited in the Lisbon area. Lipids were quantified b...

Date: 2008   |   Origin: Acta Médica Portuguesa

Mitochondrial haplogroup H1 is protective for ischemic stroke in portuguese pat...

Rosa, Alexandra; Fonseca, Benedita V.; Krug, Tiago; Manso, Helena; Gouveia, Liliana; Albergaria, Isabel; Gaspar, Gisela; Correia, Manuel

Background: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...


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