2 documents found, page 1 of 1
HIV-1 Infection in Cyprus, the Eastern Mediterranean European Frontier
Pineda-Peña, Andrea Clemencia; Theys, Kristof; Stylianou, Dora C.; Demetriades, Ioannis; Puchhammer, Elisabeth; Vandamme, Anne Mieke; Aleksiev, IvailoSince HIV-1 treatment is increasingly considered an effective preventionstrategy, it is important to study local HIV-1 epidemics to formulate tailored preventionpolicies. The prevalence of HIV-1 in Cyprus was historically low until 2005. To investigatethe shift in epidemiological trends, we studied the transmission dynamics of HIV-1 in Cyprususing a densely sampled Cypriot HIV-1 transmission cohort that include...
Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechan...
Rhee, Soo Yon; Blanco, Jose Luis; Jordan, Michael R.; Taylor, Jonathan; Lemey, Philippe; Varghese, Vici; Hamers, Raph L.; Bertagnolio, SilviaPMID: 25849352 WOS:000354825700001; Regional and subtype-specific mutational patterns of HIV-1 transmitted drug resistance (TDR) are essential for informing first-line antiretroviral (ARV) therapy guidelines and designing diagnostic assays for use in regions where standard genotypic resistance testing is not affordable. We sought to understand the molecular epidemiology of TDR and to identify the HIV-1 drug-res...