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GDF-9 and BMP-15 direct the follicle symphony

Sanfins, Alexandra; Rodrigues, Patricia; Albertini, David F.

Understanding the physiology underlying the complex dialog between the oocyte and it's surrounding somatic cells within the ovarian follicle has been crucial in defining optimal procedures for the development of clinical approaches in ART for women suffering from infertility and ovarian dysfunction. Recent studies have implicated oocyte-secreted factors like growth differentiation factor 9 (GDF-9) and bone morp...


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