6 documents found, page 1 of 1
A novel patient-derived cutaneous melanoma cell line reveals key features of me...
Tomás, Ana; Roque, Lúcia; Francisco, Inês; Silva, Ana Luísa; Nunes, Hugo; Gouveia, Emanuel; Carvalho, Elisabete; Farricha, Victor; Moura, CecíliaPublisher Copyright: Copyright © 2025 Tomás, Roque, Francisco, Silva, Nunes, Gouveia, Carvalho, Farricha, Moura, Rosa, Garrido, Albuquerque, Pereira, Cabral and Pojo.; Introduction: Cutaneous melanoma (CM) is an aggressive form of skin cancer, with rising incidence and poor prognosis at advanced stages. While early-stage CM typically carries a favorable prognosis, a small subset of patients relapses and progres...
H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management to...
Hipólito, Ana; Mendes, Cindy; Martins, Filipa; Lemos, Isabel; Francisco, Inês; Cunha, Fernando; Almodôvar, Teresa; Albuquerque, CristinaFunding Information: The institutions are funded by Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020), and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). The study was partially supported by a Merck KGaA, Darmstad...
Combining the amplification refractory mutation system and high-resolution melt...
Oliveira, Beatriz B.; Costa, Beatriz; Morão, Bárbara; Faias, Sandra; Veigas, Bruno; Pereira, Lucília Pebre; Albuquerque, Cristina; Maio, RuiPublisher Copyright: © 2023, The Author(s).; The success of personalized medicine depends on the discovery of biomarkers that allow oncologists to identify patients that will benefit from a particular targeted drug. Molecular tests are mostly performed using tumor samples, which may not be representative of the tumor’s temporal and spatial heterogeneity. Liquid biopsies, and particularly the analysis of circula...
NSCLC presents metabolic heterogeneity, and there is still some leeway for EGF ...
Mendes, Cindy; Lemos, Isabel; Francisco, Inês; Almodôvar, Teresa; Cunha, Fernando; Albuquerque, Cristina; Gonçalves, Luís G.; Serpa, JacintaFunding Information: The institutions are funded by Fundação para a Ciência e Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), to MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020) and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). Cindy Mendes was funded by a FCT individual Ph.D. fellowshi...
Pensamento, julgamento e “política do mal”
Albuquerque, CristinaUID/SOC/04647/2013; No presente artigo procuramos refletir em torno da conceção de “mal” nas sociedades democráticas modernas. O eixo analítico condutor desta reflexão centrar-se-á na relação entre uma determinada conceção de mal e os pressupostos da intencionalidade e da responsabilidade individual. Para o efeito, partiremos da tese de Arendt sobre a banalidade do mal, produzido e disseminado no âmago de regim...
Carcinoma colorectal familiar de tipo X
Ferreira, Sara; Lage, Pedro; Sousa, Rita; Claro, Isabel; Francisco, Inês; Filipe, Bruno; Suspiro, Alexandra; Chaves, Paula; Rodrigues, PaulaBackground: Some families fulfilling the Amsterdam Criteria (AC) differ from the Lynch syndrome (LS) in that colorectal cancers (CRC) do not present microsatellite instability (MSI) and DNA mismatch repair gene mutations are not found. These families have been designated as Familial Colorectal Cancer type X (XS) and their genetic basis remains unknown. Aims: In families fulfilling AC for LS: 1) To perform MSI t...