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Pearls & oy-sters: a challenging optic neuropathy: what not to miss in optic ne...

Vidal, Maria Isabel; Antunes, Ana Patrícia; Morgado, Carlos; Simas, Nuno; Roque, Rafael; Albuquerque, Luísa

Optic neuropathies include a wide range of disorders from ischemic, toxic, demyelinating, or inflammatory processes with acute/subacute onset to more gradual compressive or genetic etiologies. Accurate clinical history and multimodality optic nerve imaging including MRI and optical coherence tomography have greatly improved the diagnosis of patients with optic neuropathies. We report a case of a woman with seve...


Combined central and peripheral demyelination after COVID-19 vaccination

Coelho, Pedro; Paula, André; Martins, Isabel Vidal; Falcão De Campos, Catarina; Ferreira, João; Antunes, Ana Patrícia; Albuquerque, Luísa

Combined central and peripheral demyelination (CCPD) is a rare neurological entity that afects both the central and peripheral nervous system with demyelinating lesions. The pattern of involvement of the central nervous system (CNS) includes frequent bilateral optical neuritis, involvement of grey matter and occasional longitudinally extensive transverse myelitis (LETM) in the absence of oligoclonal bands (OCB)...


Occipital lobe seizures as presentation of an hyperglycemic state: a case report

Rodrigues, Catarina; Santos Silva, Cláudia; Coelho, Pedro; Antunes, Ana Patrícia; Falcão, Filipa; Albuquerque, Luísa

Several neurological manifestations may be associated with hyperosmotic hyperglycemic nonketotic state (HHNK). Forty percent of HHNK patients have acute symptomatic seizures, mostly focal. Motor seizures, such as epilepsia partialis continua, are the most common, while non motor ones are less recognized. Epileptic disorders of visual perception are rarely reported. We report a case of inaugural diabetes, involv...


O papel da nutrição na prevenção e tratamento de feridas

Borges, Cátia; Albuquerque, Luísa; Alves, Paulo; Ramos, Paulo; Teixeira, Abílio; Magalhães, Bruno; Mendes, Diana


Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte g...

Dias Da Costa, Mariana; Leal Rato, Miguel; Cruz, Diana; Valadas, Anabela; Antunes, Ana Patrícia; Albuquerque, Luísa

We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid ther...


Anti-glutamic acid decarboxylase encephalitis presenting with choreo‐dystonic m...

Azevedo Kauppila, Linda; Coelho, Miguel; Franco, Ana Catarina; Teodoro, Tiago; Peralta, Ana Rita; Bentes, Carla; Falcão, Filipa; Albuquerque, Luísa

Glutamic acid decarboxylase (GAD) antibodies (ab) have been associated with rare disorders, such as Stiff-person syndrome, limbic encephalitis, cerebellar ataxia, and temporal lobe epilepsy. Other systemic autoimmune disorders have been linked to antiGAD ab, among them, diabetes mellitus (DM).


Vernet syndrome resulting from varicella zoster virus infection: a very rare cl...

Ferreira, João; Franco, Ana Catarina; Teodoro, Tiago; Coelho, Miguel; Albuquerque, Luísa

Vernet syndrome is a unilateral palsy of glossopharyngeal, vagus, and accessory nerves. Varicella zoster virus (VZV) infection has rarely been described as a possible cause. A 76-year-old man presented with 1-week-long symptoms of dysphonia, dysphagia, and weakness of the right shoulder elevation, accompanied by a mild right temporal parietal headache with radiation to the ipsilateral ear. Physical examination ...


Avaliação do Estado Mental para Estimulação Cerebral Profunda: “ON” vs. “OFF”

Freitas, Vanda; Coelho, Miguel; Albuquerque, Luísa; Godinho, Catarina; Rosa, Mário Miguel; Martins, Isabel Pavão


Cerebral amyloid angiopathy associated with inflammation : report of 3 cases an...

Castro Caldas, Ana; Silva, Cristiana; Albuquerque, Luísa; Pimentel, José; Silva, Vanessa; Ferro, José

Introduction: Cerebral amyloid angiopathy associated with inflammatory process (CAA-I) is a rare potentially treatable encephalopathy, characterized by an inflammatory response to vascular deposits of b-amyloid. We aimed to describe 3 clinical cases and perform a systematic review of all neuropathologically proved CAA-I case reports to describe its clinical and pathologic features and outcome under different tr...


Delayed leukoencephalopathy after acute carbon monoxide intoxication

Geraldo, Ana Filipa; Silva, Cristiana; Neutel, Dulce; Lucas Neto, Lia; Albuquerque, Luísa

Delayed leukoencephalopathy is an uncommon complication of hypoxicischemic events of different etiologies, including carbon monoxide intoxication. We present a case of a 40-year-old male patient who was admitted with rapidly progressive neurocognitive and behavioral deficits. There was a history of accidental carbon monoxide intoxication one month before, presenting with loss of consciousness and short hospital...


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