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Complete genome sequence of two deep-sea streptomyces isolates from madeira arc...

Albuquerque, P; Ribeiro, I; Correia, S; Mucha, AP; Tamagnini, P; Braga-Henriques, A; Carvalho, MdF; Mendes, MV

The deep-sea constitutes a true unexplored frontier and a potential source of innovative drug scaffolds. Here, we present the genome sequence of two novel marine actinobacterial strains, MA3_2.13 and S07_1.15, isolated from deep-sea samples (sediments and sponge) and collected at Madeira archipelago (NE Atlantic Ocean; Portugal). The de novo assembly of both genomes was achieved using a hybrid strategy that com...


The antioxidant peptide salamandrin-i: First bioactive peptide identified from ...

Plácido, A; Bueno, J; Barbosa, EA; Moreira, DC; Dias, JDN; Cabral, WF; Albuquerque, P; Bessa, LJ; Freitas, J; Kuckelhaus, SAS; Lima, FCDA

Amphibian skin is a multifunctional organ that plays key roles in defense, breathing, and water balance. In this study, skin secretion samples of the fire salamander (Salamandra salamandra) were separated using RP-HPLC and de novo sequenced using MALDI-TOF MS/MS. Next, we used an in silico platform to screen antioxidant molecules in the framework of density functional theory. One of the identified peptides, sal...


Application of a Dot Blot Hybridization Platform to Assess Streptococcus uberis...

Albuquerque, P; Ribeiro, NJ; Almeida, A; Panschin, I; Porfirio, A; Vales, M; Diniz, F; Madeira, H; Tavares, F

Streptococcus uberis is considered one of the most important pathogens associated with bovine mastitis. While traditionally acknowledged as an environmental pathogen, S. uberis has been shown to adopt a contagious epidemiological pattern in several dairy herds. Since different control strategies are employed depending on the mode of transmission, in-depth studies of S. uberis populations are essential to determ...


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