5 documents found, page 1 of 1
Trypanocidal activity of Brazilian plants against epimastigote forms from Y and...
Alves,Renata Tomé; Regasini,Luis Octávio; Funari,Cristiano Soleo; Young,Maria Cláudia Marx; Rimoldi,Aline; Bolzani,Vanderlan da SilvaChagas disease is one of the main public health problems in Latin America. Since the available treatments for this disease are not effective in providing cure, the screening of potential antiprotozoal agents is essential, mainly of those obtained from natural sources. This study aimed to provide an evaluation of the trypanocidal activity of 92 ethanol extracts from species belonging to the families Annonaceae, ...
Intraoperative topical administration of mitomycin C, in different concentratio...
Mamede,Fabrício Villela; Martins,Bianca da Costa; Souza,Ana Letícia Groszewicz; Brunelli,Adriana Torrecilhas Jorge; Pontin,Karina; Soares,Edson GarciaMyoplasties of the extraocular muscle may cause adhesions between the operated muscle and the adjacent tissues, commonly generating cicatricial strabismus. With the purpose of reducing to a minimum the occurrence of adhesion, the effects of mitomycin C, an antifibrotic agent, were studied in concentrations of 0.008%, 0.02%, and 0.04% applied during intraoperative of myoplasties of the superior rectus muscle of ...
Piranoflavonas inéditas e atividades tripanocidas das substâncias isoladas de c...
Ambrozin,Alessandra Regina Pepe; Vieira,Paulo Cezar; Fernandes,João Batista; Silva,Maria Fátima das Graças Fernandes da; Albuquerque,Sérgio deThe phytochemical investigation of trypanocidal extracts from leaves and stems of Conchocarpus heterophyllus (A. St.-Hil.) Kallunki & Pirani (Rutaceae) afforded new pyranoflavones along with the known compounds flavone, 7-methoxyflavone, 5-hydroxyflavone, haplotusine, 1-methyl-2-phenyl-4-quinolone alkaloid, beta-sitosterol, stigmasterol, and beta-sitosteryl benzoate. Their structures were established based ...
New pyrone and quinoline alkaloid from Almeidea rubra and their trypanocidal ac...
Ambrozin,Alessandra R. P.; Mafezoli,Jair; Vieira,Paulo C.; Fernandes,João B.; Silva,M. Fátima das G. F. da; Ellena,Javier A.; Albuquerque,Sérgio deThe investigation of the ethyl acetate fraction of methanol extract from leaves of Almeidea rubra A. St.-Hil. (Rutaceae) afforded two new compounds 4-methoxy-6-[2-(methylamino)phenyl]-2H-pyran-2-one and rel-(7R,8R)-8-[(E)-3-hydroxy-3-methyl-1-butenyl]-4,8-dimethoxy-5,6,7,8 -tetrahydrofuro[2,3-b]quinoline-7-yl acetate, along with the known compounds arborinine, N-methyl-1-hydroxy-3-methoxyacridone, skimmianine, ...
Comportamento de formas sangüícolas do Trypanosoma cruzi obtidas de camundongos...
Ribeiro,Rosa Domingues; Belda Neto,Francisco Miguel; Prado Junior,José Clóvis do; Albuquerque,Sérgio deCamundongos normais, utilizados como filtros biológicos, foram inoculados endovenosamente, com tripomastigotas sangüícolas da derivada RCL da cepa RC do T. cruzi. Decorridas 48 horas, os animais foram submetidos ao xenodiagnóstico e à punção cardíaca para semeadura do sangue em meio de Warren. No estômago dos triatomíneos e em cultura a 28°C, os tripomastigotas diferenciaram-se em formas arredondadas (esferomas...