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Cyclodextrin-complexed Ocimum basilicum leaves essential oil increases Fos prot...

Nascimento, Simone de Souza; Araujo, Adriano Antunes de Souza; Brito, Renan Guedes de; Serafini, Mairim Russo; Menezes, Paula dos Passos

O. basilicum leaves produce essential oils (LEO) rich in monoterpenes. The short half-life and water insolubility are limitations for LEO medical uses. β-Cyclodextrin (β-CD) has been employed to improve the pharmacological properties of LEO. We assessed the antihyperalgesic profile of LEO, isolated or complexed in β-CD (LEO/β-CD), on an animal model for fibromyalgia. Behavioral tests: mice were treated every da...

Date: 2016   |   Origin: Oasisbr

Absorption levels and morphological features of fetal organs in wistar rats tre...

Bomfim, Kátia Michelle dos Anjos; Garcia, Carlos Alexandre Borges; Reis, Francisco Prado; Palmeira, José Arnaldo Vasconcelos; Scher, Ricardo

Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this...

Date: 2016   |   Origin: Oasisbr

CD1a-positive Langerhans cells and their relationship with E-cadherin in amelob...

Mello, Leonardo Araújo; Figueiredo, Andréia Leal; Ramos, Eduardo Antônio Gonçalves; Gurgel, Clarissa Araujo Silva; Martins, Manoela Domingues

Texto completo: acesso restrito. p. 454–461; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-26T13:36:23Z No. of bitstreams: 1 10.1111-jop.12033.pdf: 527893 bytes, checksum: bb4366150a73aa739fa0cca70070180d (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-10-10T15:10:35Z (GMT) No. of bitstreams: 1 10.1111-jop.12033.pdf: 527893 bytes, checksum: bb4366150a73aa73...

Date: 2014   |   Origin: Oasisbr

Effect of green propolis on oral epithelial dysplasia in rats

Soares, Andrea Ferreira; Cavalcante, Danielle Rodrigues Ribeiro; Oliveira, Paula Santos de; Góis, Sandro Mota; Soares, Andrea Ferreira

Studies have demonstrated that flavonoid compounds of green propolis have antitumoral activity. Study Design: Experimental study. Aims: To evaluate the effect of a hydroalcoholic extract of green propolis (EPV) on chemically induced epithelial dysplasias in rat tongues. Methods and Materials: DMBA was brushed on the lingual dorsum of rats 3x/week on alternate days - 100 (PROP1), 200 (PROP2) and 300 mg/kg (PROP3...

Date: 2014   |   Origin: Oasisbr

Efeito da própolis verde sobre displasias epiteliais orais em ratos

Soares, Andrea Ferreira; Cavalcante, Danielle Rodrigues Ribeiro; Oliveira, Paula Santos de; Góis, Sandro Mota; Cardoso, Juliana Cordeiro

Estudos têm demonstrado que componentes hidrossolúveis da própolis verde, flavonóides, apresentam atividade antitumoral. Forma de Estudo: Estudo experimental. Objetivo: Avaliar o efeito do extrato hidroalcoólico de própolis verde (EPV) sobre displasias epiteliais linguais quimicamente induzidas em ratos. Materiais e Métodos: Neste estudo, foi pincelado DMBA (9,10-dimetil-1,2-benzatraceno) no dorso lingual de ra...

Date: 2014   |   Origin: Oasisbr

Desmoplastic ameloblastoma mimicking a periapical lesion

Soares, Andrea Ferreira; Santos, Esaú Pinheiro dos; Araújo, Francisco Emanuel N.; Valido, Daisy Pereira; Lima, Sônia Oliveira

OBJETIVO: Ameloblastoma desmoplásico (AD) é uma rara variante do ameloblastoma, com características clínicas, imaginológicas e histopatológicas específicas. O perfil biológico deste tumor não é totalmente compreendido, devido ao número limitado de casos notificados. O objetivo deste trabalho é relatar um caso de AD simulando uma lesão periapical. DESCRIÇÃO DO CASO: Este tumor apareceu na região anterior da maxi...

Date: 2014   |   Origin: Oasisbr

Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalb...

Melo, Marcelia Garcez Dória de; Araújo, Adriano Antunes de Souza; Serafini, Mairim Russo; Carvalho, Larissa Feitosa; Bezerra, Marília dos Santos

Atranorin (ATR) is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was ind...

Date: 2013   |   Origin: Oasisbr

Antinociceptive activity and toxicological study of aqueous extract of Egletes ...

Araújo, Adriano Antunes de Souza; Bonjardim, Leonardo Rigoldi; Mota, Érica Mendonça; Albuquerque Júnior, Ricardo Luiz Cavalcanti de

Egletes viscosa Less (Asteraceae), popularly known as "macela" or "macela-da-terra", is a plant widely used in popular medicine due to its anti-inflammatory, bactericidal, antidiarrhoea, mio-relaxant, antispasmodic, antinociceptive, digestive, and anti-viral properties. Phytochemical screening of aqueous extract of Egletes viscosa (AEEV) revealed the high presence of flavonoids. This study examined the oral ant...

Date: 2013   |   Origin: Oasisbr

Pre-clinical toxicity of Morinda citrifolia Linn. leaf extract

Serafini, Mairim Russo; Santos, Rodrigo Correia; Dória, Grace Anne Azevedo; Jesus, Josepha Yohanna de; Melo, Marcelia Garcez Dória de

This investigation was carried out to evaluate the safety of an aqueous extract of Morinda citrifolia leaves (AEMC) by determining its potential toxicity after acute administration (5 g/kg) in rodents and cytotoxic studies. General behavior adverse effects and mortality were determined for up to 14 days. Biochemical and hematological parameters were determined after 14 days. Cytotoxic effects of the AEMC were d...

Date: 2013   |   Origin: Oasisbr

Improvement of dermal burn healing by combining sodium alginate/chitosan-based ...

Pinheiro, Antonio Luiz Barbosa; Albuquerque Júnior, Ricardo Luiz Cavalcanti de; Cavalcante, Danielle Rodrigues Ribeiro; Ribeiro, Maria Amalia Gonzaga

texto completo. acesso restrito. p. 51–59.; Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-02-23T16:34:53Z No. of bitstreams: 1 __pdn.sciencedirect.com_....0-S1011134411001606-main.pdf: 782766 bytes, checksum: df7135630424d985e197b407c9a83e67 (MD5); Made available in DSpace on 2012-02-23T16:34:53Z (GMT). No. of bitstreams: 1 __pdn.sciencedirect.com_....0-S1011134411001606-main.pdf:...

Date: 2012   |   Origin: Oasisbr

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