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Genetic and microenvironmental intra-tumor heterogeneity impacts colorectal can...

Sobral, Daniel; Martins, Marta; Kaplan, Shannon; Golkaram, Mahdi; Salmans, Michael; Khan, Nafeesa; Vijayaraghavan, Raakhee; Casimiro, Sandra

We thank João Neto and remaining Computational Multi-Omics Lab members at UCIBIO for their helpful comments and suggestions. © 2022. The Author(s).; Colorectal cancer (CRC) is a highly diverse disease, where different genomic instability pathways shape genetic clonal diversity and tumor microenvironment. Although intra-tumor heterogeneity has been characterized in primary tumors, its origin and consequences in ...

Date: 2022   |   Origin: Repositório Institucional da UNL
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