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Determinants of HIV-1 Transmission Clusters and Transmitted Drug Resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N S; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

Introduction: In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determina...


Determinants of HIV-1 transmission clusters and transmitted drug resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N. S.; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM new...


SAFETY AND EFFICACY OF DOLUTEGRAVIR BASED TRIPLE THERAPY IN HIV-2 INFECTION

Lopes, Maria João; Pacheco, Patrícia; Marques, Nuno; Mansinho, Kamal; Araújo, Vânia; Janeiro, Nuno; Lopes, Cristina; Rodrigues, Paulo; Maltez, Fernando

Database solution for an HIV-2 cohort study Publication "Real-world experience of TAF/FTC/BIC in people with HIV-2" presented at European AIDS Clinical Society Conference, Oct 2023, Warsaw HIV-2 salvage therapy with Lenacapavir (injectable, capsid inhibitor, EMA approved 2022)


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction: HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019. Methods: We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral q...


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019.Methods We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral ques...


HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...

Pingarilho, Marta; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca Branco; Piñeiro, Carmela; Koch, Carmo

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


HIV-1-transmitted drug resistance and transmission clusters in newly diagnosed ...

Pingarilho, Marta; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca Branco; Piñeiro, Carmela; Koch, Carmo

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


Frequência de Mutações de Resistência aos ARVs em novos casos de infeção por VI...

Aldir, Isabel; Cortes Martins, Helena; Caetano, Constantino; Sarmento, António; Serrão, Rosário; Saraiva da Cunha, José; Oliveira, Joaquim

Introdução: A avaliação da presença de mutações que confiram resistência aos fármacos usados no tratamento da infeção por VIH-1, faz parte da avaliação laboratorial efetuada no quadro de um diagnóstico de novo, e a monitorização da sua prevalência é preconizada internacionalmente. Objetivos: Avaliar a frequência de mutações de resistência (MR) entre doentes com diagnóstico estabelecido em 2018 e identificar det...


Two cases of dolutegravir failure with R263K mutation

Cardoso, Margarida; Baptista, Teresa; Diogo, Isabel; Aleixo, Maria João; Marques, Nuno; Mansinho, Kamal; Gomes, Perpétua


Traveler's diarrhea

Aleixo, Maria João

A traveler coming from a developed country is at greater risk of developing diarrhea to move to tropical or subtropical countries, usually less developed, for a traveler natural regions of the latter.; Um viajante oriundo de um país desenvolvido corre maior risco de desenvolver diarreia ao deslocar-se para países tropicais ou subtropicais, geralmente menos desenvolvidos, relativamente a um viajante natural dess...


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