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Glutamine and Alanyl-Glutamine increase RhoA expression and reduce clostridium ...

Santos, Ana Angélica Queiroz Assunção; Braga Neto, Manuel Bonfim; Oliveira, Marcelo Róseo de; Freire, Rosemayre Souza; Barros, Eduardo Bedê

Clostridium difficile is a major cause of antibiotic-associated colitis and is associated with signicant morbidity and mortality. Glutamine (Gln) is a major fuel for the intestinal cell population. Alanyl-glutamine (Ala-Gln) is a dipeptide that is highly soluble and well tolerated. IEC-6 cells were used in the in vitro experiments. Cell morphology was evaluated by atomic force microscopy (AFM) and scanning elec...

Date: 2020   |   Origin: Oasisbr

Estudo morfológico e das propriedades elásticas de plaquetas humanas por micros...

Alencar, Luciana Magalhães Rebêlo

The platelets have a major rule in processes like hemostasis and thrombosis. They go through drastic changes in their structure in such events, which includes alterations in shape from a circular outline to a completely amorphous profile. Therefore, this cellular restructuration is strongly linked to citoesqueleton rearrangement, affecting the whole structure localizes under the plasmatic membrane, which is res...

Date: 2015   |   Origin: Oasisbr

Estudo da viscoelasticidade de células de câncer renal por microscopia de força...

Alencar, Luciana Magalhães Rebêlo

The mechanical properties of living cells have a crucial role in the accomplishment of their physiological functions. However, our knowledge on this subject is still limited. Is not fully understood how a cell responds structurally and mechanically to an external pressure or as the elasticity of cells is altered in diseased organisms compared to healthy ones. Recently, the biomechanics of cancer cells, in parti...

Date: 2015   |   Origin: Oasisbr

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